Khatua Anupam, Pal Debprasad, Kar Tapan Kumar
Department of Mathematics, Indian Institute of Engineering Science and Technology, Shibpur, Howrah, 711103 India.
Department of Mathematics, Bethune College, 181 Bidhan Sarani, Kolkata, 700006 India.
Iran J Sci Technol Trans A Sci. 2022;46(3):859-868. doi: 10.1007/s40995-022-01287-5. Epub 2022 May 13.
In this article, we investigate a diffusive two-strain epidemic model with non-monotone incidence rate and virus mutation. The positivity, existence and uniform boundedness of the solutions of the model system are studied. It is found that the system has three equilibrium points, namely the infection-free equilibrium point, the strain-2 endemic equilibrium point and both the strain-1 and strain-2 endemic equilibrium points. The global asymptotic stability analysis of the diffusive model system near all the equilibrium points is carried out by constructing appropriate Lyapunov functional. It is found that the system has no strain-1 endemic equilibrium point possibly due to the virus mutation. So, in this type of diseases, the infection due to strain-1 cannot be persistent in the community.
在本文中,我们研究了一个具有非单调发病率和病毒突变的扩散两菌株流行病模型。研究了该模型系统解的正性、存在性和一致有界性。发现该系统有三个平衡点,即无感染平衡点、菌株2地方病平衡点以及菌株1和菌株2地方病平衡点。通过构造适当的Lyapunov泛函,对扩散模型系统在所有平衡点附近进行了全局渐近稳定性分析。发现该系统可能由于病毒突变而没有菌株1地方病平衡点。因此,在这类疾病中,菌株1引起的感染在社区中不可能持续存在。