Manhas Monica, Koul Disha, Kalsotra Gopika, Manhas Amit, Kalsotra Parmod, Kumar Parmil, Bhat Abid, Gupta Anchal, Saraf Aditya
Department of Physiology, Government Medical College, Jammu, Jammu and Kashmir, India.
Department of ENT and Head and Neck Surgery, SMGS Hospital, Government Medical College, Jammu, Jammu and Kashmir, India.
Int Arch Otorhinolaryngol. 2022 May 20;26(2):e265-e271. doi: 10.1055/s-0042-1743274. eCollection 2022 Apr.
Coronavirus disease 2019 (COVID-19) is a dangerous infectious disease caused by a newly discovered severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that has various clinical presentations. Numerable cases with non-specific olfactory and gustatory dysfunctions in COVID-19 have been reported from all over the globe. This is important as awareness will let people to self-isolate and help in limiting disease spread. To objectively evaluate the frequency of olfactory and gustatory dysfunction, which may occur independently or with other symptoms, in laboratory confirmed COVID-19 patients at an early stage of the disease. Objective evaluation of olfactory and gustatory function of 322 COVID-19 patients treated at our hospital, (SMGS, Government Medical College, Jammu), from August 2020 until November 2020. Our study population included 127 (39.4%) males and 195 (60.6%) females. Two hundred and twenty-six (70.2%) COVID-19 patients experienced olfactory and gustatory disorders. One hundred and sixty-five (51.2%) cases experienced both olfactory and gustatory disorders. Isolated olfactory dysfunction was reported in 34 (10.6%) patients, while 27 (8.4%) patients experienced only gustatory dysfunction. The olfactory and gustatory dysfunctions, without any nasal obstruction or rhinorrhea, are significant symptoms in the clinical presentation of early COVID-19 patients. This presentation can be recognized at the earliest one, and it can reduce the high communicability of the COVID-19 disease.
2019冠状病毒病（COVID-19）是一种由新发现的严重急性呼吸综合征冠状病毒2（SARS-CoV-2）引起的危险传染病，具有多种临床表现。全球各地都报告了大量COVID-19患者出现非特异性嗅觉和味觉功能障碍的病例。这一点很重要，因为提高认识将使人们能够自我隔离并有助于限制疾病传播。
为了客观评估在实验室确诊的COVID-19患者疾病早期可能独立出现或与其他症状同时出现的嗅觉和味觉功能障碍的发生率。
对2020年8月至2020年11月期间在我院（查谟政府医学院SMGS）接受治疗的322例COVID-19患者的嗅觉和味觉功能进行客观评估。
我们的研究人群包括127名（39.4%）男性和195名（60.6%）女性。226名（70.2%）COVID-19患者出现嗅觉和味觉障碍。165名（51.2%）患者同时出现嗅觉和味觉障碍。34名（10.6%）患者报告有孤立性嗅觉功能障碍，而27名（8.4%）患者仅出现味觉功能障碍。
在早期COVID-19患者的临床表现中，无任何鼻塞或流涕的嗅觉和味觉功能障碍是重要症状。这种表现最早可在第一时间被识别，并且可以降低COVID-19疾病的高传染性。
