Chaturvedi Himani Tiwari, Patel Varsha Prabhubhai, Vasava Rahul Ramanbhai, Chaturvedi Chandrashekher
Department of Oral Pathology, Dharmsinh Desai University, Nadiad, Gujarat, India.
Department of Medicine, SSG Medical College, Vadodara, Gujarat, India.
J Oral Maxillofac Pathol. 2021 Jan-Apr;25(1):12-17. doi: 10.4103/jomfp.jomfp_88_21. Epub 2021 May 14.
Coronavirus disease-2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), may be associated with acute onset of smell and taste dysfunction along with other common presenting symptoms such as cough, fever and myalgia. Our study aims to analyze the presence of olfactory and gustatory dysfunctions Olfactory and gustatory dysfunctions (OGDs) in patients with COVID-19 and to assess their onset and recovery.
The cross-sectional study was conducted in March 2021 retrospectively at Care Multispecialty Hospital, Vadodara. A total 301 patients were admitted, among those 280 qualify according to inclusion criteria and 3 patients denied to participate in the study. All patients presenting with laboratory-confirmed real-time reverse transcriptase polymerase chain reaction test for SARS-CoV-2 were included in the study. All 277 patients were undergone a diagnostic questionnaire through telephonic conversation which include patient main symptoms and self-assessment of loss of smell and taste and their onset and recovery.
Two hundred and seventy-seven patients were included in this study. One hundred and fifty-three patients (55%) reported olfactory and gustatory disorders. Loss of taste and smell were more frequently reported in female patients (72.8%) than male patients (48%). Onset of these symptoms concomitant with other typical symptoms of COVID-19 is in 58.2% of cases. Recovery of symptoms in most patients was in 5-10 days and faster in younger patients.
Olfactory and gustatory disorders (OGDs) related to COVID-19 are frequently reported and more common in female patients. Rapid recovery was observed in most cases. Altogether OGDs can possibly act pivot screening or diagnostic tool for COVID-19 pandemic.
2019冠状病毒病（COVID-19）由严重急性呼吸综合征冠状病毒2（SARS-CoV-2）引起，可能与嗅觉和味觉功能障碍的急性发作以及咳嗽、发热和肌痛等其他常见症状有关。我们的研究旨在分析COVID-19患者中嗅觉和味觉功能障碍（OGD）的存在情况，并评估其发作和恢复情况。
这项横断面研究于2021年3月在瓦多达拉的关爱多专科医院进行回顾性研究。共收治301例患者，其中280例符合纳入标准，3例拒绝参与研究。所有经实验室确诊为SARS-CoV-2实时逆转录聚合酶链反应检测阳性的患者均纳入研究。所有277例患者通过电话访谈接受了一份诊断问卷，问卷包括患者的主要症状、嗅觉和味觉丧失的自我评估及其发作和恢复情况。
本研究纳入277例患者。153例患者（55%）报告有嗅觉和味觉障碍。女性患者（72.8%）比男性患者（48%）更频繁地报告味觉和嗅觉丧失。这些症状与COVID-19的其他典型症状同时出现的情况占58.2%。大多数患者的症状在5至10天内恢复，年轻患者恢复得更快。
与COVID-19相关的嗅觉和味觉障碍（OGD）报告频繁，在女性患者中更常见。大多数病例观察到快速恢复。总体而言，OGD可能作为COVID-19大流行的关键筛查或诊断工具。
