General Secretary and National Head of Laser Department of ISPLAD, International-Italian Society of Plastic-Regenerative and Oncologic Dermatology, Verona, Italy.
Biologist-Florence-Italy, Florence, Italy.
Photobiomodul Photomed Laser Surg. 2022 Jun;40(6):424-432. doi: 10.1089/photob.2021.0165. Epub 2022 May 24.
The mechanism of action of fractional carbon dioxide (CO) laser in the management of skin scarring is stimulation of collagen and fibroblasts in the dermis, resulting in remodeling and shrinking of the skin. The purpose of this research is to assess the safety and performance of a new CO laser scanner for treatment of acne scars. The study was carried out on 20 patients of both sexes, with a mean age of 25.7 ± 6.7 years. To assess the performance and safety of this new CO scanner, a preclinical histological evaluation was done. A clinical evaluation of acne scars was performed using Goodman and Baron's quantitative global acne scarring grading system (GBQGASGS) and a crusting scale where crusting scores ranged from 1 = none to 4 = severe. Digital photographs were taken to obtain esthetic results. GBQGASGS showed a significant improvement in patients' scars and the treatment was well tolerated, with no lasting side effects. The new scanner seems to be an effective and safe device for skin scarring treatment, speeding up the healing time of scars.
分段二氧化碳（CO）激光治疗皮肤瘢痕的作用机制是刺激真皮中的胶原和成纤维细胞，导致皮肤重塑和收缩。本研究旨在评估一种新型 CO 激光扫描仪治疗痤疮瘢痕的安全性和疗效。研究对象为 20 名男女患者，平均年龄为 25.7±6.7 岁。为了评估这种新型 CO 扫描仪的性能和安全性，进行了临床前组织学评估。使用 Goodman 和 Baron 的定量全球痤疮瘢痕分级系统（GBQGASGS）和结痂量表对痤疮瘢痕进行临床评估，结痂评分范围为 1=无到 4=严重。拍摄数码照片以获得美学效果。GBQGASGS 显示患者的瘢痕有显著改善，且治疗耐受性良好，无持久的副作用。新型扫描仪似乎是一种有效且安全的皮肤瘢痕治疗设备，可加快瘢痕的愈合时间。
