Kamiński Bartłomiej, Błochowiak Katarzyna, Kołomański Konrad, Sikora Maciej, Karwan Sławomir, Chlubek Dariusz
Department of Otolaryngology, Maria Skłodowska-Curie District Hospital, 26-110 Skarżysko-Kamienna, Poland.
Department of Oral Surgery and Periodontology, Poznan University of Medical Sciences, 61-701 Poznan, Poland.
J Clin Med. 2022 May 12;11(10):2731. doi: 10.3390/jcm11102731.
The treatment of oral and maxillofacial infections is based on a recognized algorithm that may require modification under the influence of various local and systemic factors. The aim of this study was to present a comprehensive and microbiological profile of oral and maxillofacial infections, and explore possible correlations between the course of an infection and selected systemic factors based on the medical records of 329 patients affected by the disease. We identified most common clinical, demographic, bacterial, and laboratory parameters specific for these infections. There were statistically significant differences in Erythrocyte Sedimentation Rate, number of accompanying diseases, otalgia, dyspnea, and speech difficulties occurrence and neck space involvement between diabetic and non-diabetic patients. The duration of hospitalization and accompanying diseases correlated positively with the patient age and white blood cell count, and C-reactive protein value negatively correlated with age. The primary cause of infections, age, and comorbid diseases can modify the infection course and increase the risk of developing serious complications. It confirms the need for effective and targeted bacterial treatment in the early stages of infections. Age and general diseases are the most important systemic factors determining the infection symptoms and laboratory parameters assessing the severity of the inflammatory process.
口腔颌面部感染的治疗基于一种公认的算法，该算法可能需要在各种局部和全身因素的影响下进行调整。本研究的目的是呈现口腔颌面部感染的全面微生物学概况，并根据329例受该疾病影响患者的病历，探讨感染病程与选定全身因素之间的可能相关性。我们确定了这些感染特有的最常见临床、人口统计学、细菌学和实验室参数。糖尿病患者和非糖尿病患者在红细胞沉降率、伴随疾病数量、耳痛、呼吸困难、言语困难发生率以及颈部间隙受累方面存在统计学显著差异。住院时间和伴随疾病与患者年龄和白细胞计数呈正相关，而C反应蛋白值与年龄呈负相关。感染的主要原因、年龄和合并疾病可改变感染病程并增加发生严重并发症的风险。这证实了在感染早期进行有效和针对性细菌治疗的必要性。年龄和全身性疾病是决定感染症状以及评估炎症过程严重程度的实验室参数的最重要全身因素。
