卡泊芬净用于治疗与……相关的尿路感染的病例系列结果 。（原文中“-related”处信息缺失）
Outcomes of caspofungin use in the treatment of -related urinary tract infections, a case series.
作者信息
Rkieh Laila, El Nekidy Wasim S, Alsoud Leen Oyoun, Alatoom Adnan, El Lababidi Rania, Mooty Mohamad, Nusair Ahmad R
机构信息
Trillium Health Partners Mississauga Hospital, Mississauga, ON, Canada.
Cleveland Clinic Abu Dhabi, Abu Dhabi, United Arab Emirates.
出版信息
IDCases. 2022 May 18;28:e01510. doi: 10.1016/j.idcr.2022.e01510. eCollection 2022.
Abstract
Echinocandins are generally excluded in the treatment of related urinary tract infections due to their poor urinary concentration. In the presence of fluconazole resistant species, such as and , alternative therapies are needed. We herein report the use of caspofungin for the treatment of 10 patients with candiduria, including . Mycological cure was achieved in 6 of 7 patients and clinical cure was achieved in 8 of 10 patients. Larger studies are needed to confirm our findings.
摘要
由于棘白菌素在尿液中的浓度较低，通常不用于治疗相关的尿路感染。在存在对氟康唑耐药的菌种（如[具体菌种1]和[具体菌种2]）时，需要替代疗法。我们在此报告使用卡泊芬净治疗10例念珠菌尿患者，包括[具体病例情况]。7例患者中有6例实现了真菌学治愈，10例患者中有8例实现了临床治愈。需要更大规模的研究来证实我们的发现。
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