卡泊芬净用于治疗与……相关的尿路感染的病例系列结果 。（原文中“-related”处信息缺失）
Outcomes of caspofungin use in the treatment of -related urinary tract infections, a case series.
作者信息
Rkieh Laila, El Nekidy Wasim S, Alsoud Leen Oyoun, Alatoom Adnan, El Lababidi Rania, Mooty Mohamad, Nusair Ahmad R
机构信息
Trillium Health Partners Mississauga Hospital, Mississauga, ON, Canada.
Cleveland Clinic Abu Dhabi, Abu Dhabi, United Arab Emirates.
出版信息
IDCases. 2022 May 18;28:e01510. doi: 10.1016/j.idcr.2022.e01510. eCollection 2022.
Abstract
Echinocandins are generally excluded in the treatment of related urinary tract infections due to their poor urinary concentration. In the presence of fluconazole resistant species, such as and , alternative therapies are needed. We herein report the use of caspofungin for the treatment of 10 patients with candiduria, including . Mycological cure was achieved in 6 of 7 patients and clinical cure was achieved in 8 of 10 patients. Larger studies are needed to confirm our findings.
摘要
由于棘白菌素在尿液中的浓度较低，通常不用于治疗相关的尿路感染。在存在对氟康唑耐药的菌种（如[具体菌种1]和[具体菌种2]）时，需要替代疗法。我们在此报告使用卡泊芬净治疗10例念珠菌尿患者，包括[具体病例情况]。7例患者中有6例实现了真菌学治愈，10例患者中有8例实现了临床治愈。需要更大规模的研究来证实我们的发现。
相似文献
1
Outcomes of caspofungin use in the treatment of -related urinary tract infections, a case series.
IDCases. 2022 May 18;28:e01510. doi: 10.1016/j.idcr.2022.e01510. eCollection 2022.
2
High prevalence of asymptomatic nosocomial candiduria due to among hospitalized patients with heart failure: a matter of some concern?
Curr Med Mycol. 2020 Dec;6(4):1-8. doi: 10.18502/cmm.6.4.5327.
3
Successful treatment with caspofungin of candiduria in a child with Wilms tumor; review of literature.
J Mycol Med. 2017 Jun;27(2):261-265. doi: 10.1016/j.mycmed.2017.01.006. Epub 2017 Feb 8.
4
Caspofungin irrigation through percutaneous calicostomy catheter combined with oral flucytosine to treat fluconazole-resistant symptomatic candiduria.
J Mycol Med. 2015 Mar;25(1):87-90. doi: 10.1016/j.mycmed.2014.12.003. Epub 2015 Jan 31.
5
Caspofungin in the treatment of symptomatic candiduria.
Clin Infect Dis. 2007 Mar 1;44(5):e46-9. doi: 10.1086/510432. Epub 2007 Jan 22.
6
Candida and candidaemia. Susceptibility and epidemiology.
Dan Med J. 2013 Nov;60(11):B4698.
7
Treatment of candiduria with micafungin: A case series.
Can J Infect Dis Med Microbiol. 2007 Mar;18(2):149-50. doi: 10.1155/2007/768734.
8
Limitations of caspofungin in the treatment of obstructive pyonephrosis due to Candida glabrata infection.
BMC Infect Dis. 2006 Aug 8;6:126. doi: 10.1186/1471-2334-6-126.
9
In vitro Synergistic Activity of Caspofungin Plus Polymyxin B Against Fluconazole-Resistant Candida glabrata.
Am J Med Sci. 2016 Mar;351(3):265-70. doi: 10.1016/j.amjms.2015.12.014.
10
Distribution and antifungal susceptibility of Candida species causing nosocomial candiduria.
Med Mycol. 2012 Jul;50(5):529-32. doi: 10.3109/13693786.2011.618996. Epub 2011 Oct 11.
引用本文的文献
1
Drug analysis of a fatal case of bloodstream infection combined with urinary tract infection due to echinocandin-resistant .
IDCases. 2025 May 9;40:e02261. doi: 10.1016/j.idcr.2025.e02261. eCollection 2025.
2
Candida albicans and Antifungal Peptides.
Infect Dis Ther. 2023 Dec;12(12):2631-2648. doi: 10.1007/s40121-023-00889-9. Epub 2023 Nov 8.
本文引用的文献
1
Treatment of recurrent urinary tract infections in anuric hemodialysis patient, do we really need antimicrobial urinary concentration?
IDCases. 2020 Mar 21;20:e00748. doi: 10.1016/j.idcr.2020.e00748. eCollection 2020.
2
Epidemiology of candiduria and Candida urinary tract infections in inpatients and outpatients: results from a 10-year retrospective survey.
Cent European J Urol. 2019;72(2):209-214. doi: 10.5173/ceju.2019.1909. Epub 2019 Jun 29.
3
Candiduria: Evidence-based approach to management, are we there yet?
J Mycol Med. 2017 Sep;27(3):293-302. doi: 10.1016/j.mycmed.2017.04.005. Epub 2017 May 10.
4
Micafungin treatment and eradication of candiduria among hospitalized patients.
Int Urol Nephrol. 2016 Nov;48(11):1881-1885. doi: 10.1007/s11255-016-1410-0. Epub 2016 Sep 1.
5
Urinary micafungin levels are sufficient to treat urinary tract infections caused by Candida spp.
Int J Antimicrob Agents. 2016 Aug;48(2):212-4. doi: 10.1016/j.ijantimicag.2016.05.010. Epub 2016 Jul 5.
6
Clinical Practice Guideline for the Management of Candidiasis: 2016 Update by the Infectious Diseases Society of America.
Clin Infect Dis. 2016 Feb 15;62(4):e1-50. doi: 10.1093/cid/civ933. Epub 2015 Dec 16.
7
The epidemiology of bacteriuria and candiduria in critically ill patients.
Epidemiol Infect. 2015 Feb;143(3):653-62. doi: 10.1017/S0950268814000934. Epub 2014 Apr 24.
8
Candiduria: prevalence and trends in antifungal susceptibility in a tertiary care hospital of mangalore.
J Clin Diagn Res. 2013 Nov;7(11):2459-61. doi: 10.7860/JCDR/2013/6298.3578. Epub 2013 Nov 10.
9
Candida urinary tract infection and Candida species susceptibilities to antifungal agents.
J Antibiot (Tokyo). 2013 Nov;66(11):651-4. doi: 10.1038/ja.2013.68. Epub 2013 Jun 26.
10
Candida urinary tract infections--treatment.
Clin Infect Dis. 2011 May;52 Suppl 6:S457-66. doi: 10.1093/cid/cir112.
Zotero 插件