Rkieh Laila, El Nekidy Wasim S, Alsoud Leen Oyoun, Alatoom Adnan, El Lababidi Rania, Mooty Mohamad, Nusair Ahmad R
Trillium Health Partners Mississauga Hospital, Mississauga, ON, Canada.
Cleveland Clinic Abu Dhabi, Abu Dhabi, United Arab Emirates.
IDCases. 2022 May 18;28:e01510. doi: 10.1016/j.idcr.2022.e01510. eCollection 2022.
Echinocandins are generally excluded in the treatment of related urinary tract infections due to their poor urinary concentration. In the presence of fluconazole resistant species, such as and , alternative therapies are needed. We herein report the use of caspofungin for the treatment of 10 patients with candiduria, including . Mycological cure was achieved in 6 of 7 patients and clinical cure was achieved in 8 of 10 patients. Larger studies are needed to confirm our findings.
由于棘白菌素在尿液中的浓度较低，通常不用于治疗相关的尿路感染。在存在对氟康唑耐药的菌种（如[具体菌种1]和[具体菌种2]）时，需要替代疗法。我们在此报告使用卡泊芬净治疗10例念珠菌尿患者，包括[具体病例情况]。7例患者中有6例实现了真菌学治愈，10例患者中有8例实现了临床治愈。需要更大规模的研究来证实我们的发现。
