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1990年至2019年全球各地区艾滋病毒/艾滋病负担的时空趋势：全球疾病负担研究2019的二次分析

Spatial and Temporal Trends in HIV/AIDS Burden Among Worldwide Regions From 1990 to 2019: A Secondary Analysis of the Global Burden of Disease Study 2019.

作者信息

He Huan, Ou Zejin, Yu Danfeng, Li Yongzhi, Liang Yuanhao, He Wenqiao, Gao Yuhan, Wu Fei, Chen Qing

机构信息

Guangdong Provincial Key Laboratory of Tropical Disease Research, Department of Epidemiology, School of Public Health, Southern Medical University, Guangzhou, China.

Key Laboratory of Occupational Environment and Health, Guangzhou Twelfth People's Hospital, Guangzhou, China.

出版信息

Front Med (Lausanne). 2022 May 12;9:808318. doi: 10.3389/fmed.2022.808318. eCollection 2022.

DOI:10.3389/fmed.2022.808318
PMID:35646986
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9133478/
Abstract

PURPOSE

HIV/AIDS is a critical public health concern worldwide. This article investigated the spatial and temporal trends in HIV/AIDS burden from 1990 to 2019.

METHODS

Data were extracted from the Global Burden of Disease (GBD) Study 2019. The estimated annual percentage change (EAPC) and the age-standardized rate (ASR) were used to quantify the change in trends at the global, regional, and national levels.

RESULTS

In terms of temporal trends, during the period 1990-2004, increasing trends in prevalence (EAPC = 7.47, 95% confidence interval [CI] 5.84, 9.12), death (EAPC = 10.85, 95% CI 8.90-12.84), and disability-adjusted life years (DALYs) (EAPC = 10.40, 95% CI 8.47-12.36) of HIV/AIDS were observed. During the period 2005-2019, the global trends in HIV/AIDS incidence, death, and DALYs of HIV/AIDS decreased, with the EAPCs of -2.68 (95% CI-2.82--2.53), -6.73 (95% CI -6.98--6.47), and -6.75 (95% CI -6.95--6.54), respectively. However, the disease prevalence showed a slight increasing trend (EAPC = 0.71, 95% CI 0.54-0.87). In terms of spatial trends, over the past 15 years, trends in HIV/AIDS incidence of HIV/AIDS appeared upward in High-middle and High sociodemographic index (SDI) areas (EAPC = 6.51, 95% CI 5.50-7.53; EAPC = 2.31, 95% CI 2.02-2.60, respectively).

CONCLUSION

Decreasing trends in HIV/AIDS incidence, death, and DALYs have been observed worldwide over the past 15 years, especially in death and DALYs rates. However, the global population living with HIV/AIDS is still increasing. It is worth noting that an unfavorable trend emerged in High-middle and High SDI areas. Prevention and control of HIV/AIDS still need to be strengthened to counteract these concerning trends.

摘要

目的

艾滋病毒/艾滋病是全球重要的公共卫生问题。本文调查了1990年至2019年艾滋病毒/艾滋病负担的时空趋势。

方法

数据摘自《2019年全球疾病负担研究》。使用估计年变化率（EAPC）和年龄标准化率（ASR）来量化全球、区域和国家层面趋势的变化。

结果

在时间趋势方面，1990 - 2004年期间，艾滋病毒/艾滋病的患病率（EAPC = 7.47，95%置信区间[CI] 5.84，9.12）、死亡率（EAPC = 10.85，95% CI 8.90 - 12.84）和伤残调整生命年（DALYs）（EAPC = 10.40，95% CI 8.47 - 12.36）呈上升趋势。在2005 - 2019年期间，艾滋病毒/艾滋病的发病率、死亡率和DALYs的全球趋势下降，EAPC分别为-2.68（95% CI -2.82 - -2.53）、-6.73（95% CI -6.98 - -6.47）和-6.75（95% CI -6.95 - -6.54）。然而，疾病患病率呈轻微上升趋势（EAPC = 0.71，95% CI 0.54 - 0.87）。在空间趋势方面，在过去15年中，艾滋病毒/艾滋病的发病率在高中社会人口指数（SDI）地区呈上升趋势（EAPC = 6.51，95% CI 5.50 - 7.53；EAPC = 2.31，95% CI 2.02 - 2.60）。

结论

在过去15年中，全球范围内艾滋病毒/艾滋病的发病率、死亡率和DALYs呈下降趋势，尤其是死亡率和DALYs率。然而，全球感染艾滋病毒/艾滋病的人口仍在增加。值得注意的是，在高中SDI地区出现了不利趋势。仍需加强艾滋病毒/艾滋病的预防和控制，以应对这些令人担忧的趋势。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1d37/9133478/3daa89e6619a/fmed-09-808318-g0005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1d37/9133478/00ec7f6aebc2/fmed-09-808318-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1d37/9133478/b8fc72b1eddf/fmed-09-808318-g0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1d37/9133478/f1d6234f7dbb/fmed-09-808318-g0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1d37/9133478/cc2c16b828e8/fmed-09-808318-g0004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1d37/9133478/3daa89e6619a/fmed-09-808318-g0005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1d37/9133478/00ec7f6aebc2/fmed-09-808318-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1d37/9133478/b8fc72b1eddf/fmed-09-808318-g0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1d37/9133478/f1d6234f7dbb/fmed-09-808318-g0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1d37/9133478/cc2c16b828e8/fmed-09-808318-g0004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1d37/9133478/3daa89e6619a/fmed-09-808318-g0005.jpg

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