Friberg T R, Sanborn G, Weinreb R N
Am J Ophthalmol. 1987 Apr 15;103(4):523-6. doi: 10.1016/s0002-9394(14)74275-8.
We measured intraocular and episcleral venous pressure in 11 subjects in both the supine and the head-down vertical position. Gonioscopy was performed in eight subjects. The intraocular pressure changes were correlated with the alterations in episcleral venous pressure using linear regression analysis. We found that for each 0.83 +/- 0.21 mm Hg increase in episcleral venous pressure there was a rise of 1 mm Hg in intraocular pressure (r = .80, P = .003). Upon inversion, blood appeared in Schlemm's canal in half of the eyes studied with gonioscopy, suggesting that it refluxed into the canal from increased episcleral venous pressure. The mechanism of a sustained intraocular pressure rise during gravity inversion appears to be closely related to increased venous pressure in the orbit.
我们在11名受试者处于仰卧位和头低位垂直位时测量了眼内压和巩膜上静脉压。对8名受试者进行了前房角镜检查。使用线性回归分析将眼内压变化与巩膜上静脉压的改变相关联。我们发现，巩膜上静脉压每升高0.83±0.21 mmHg，眼内压就升高1 mmHg（r = 0.80，P = 0.003）。在进行前房角镜检查的半数眼睛中，倒置时施莱姆管内出现血液，这表明血液因巩膜上静脉压升高而回流至该管。重力倒置期间眼内压持续升高的机制似乎与眼眶内静脉压升高密切相关。
