与冷却塔相关的庞蒂亚克热暴发
Pontiac fever outbreak associated with a cooling tower.
作者信息
Friedman S, Spitalny K, Barbaree J, Faur Y, McKinney R
出版信息
Am J Public Health. 1987 May;77(5):568-72.
Abstract
In late April 1984, an outbreak of Pontiac fever was investigated in an office building in lower Manhattan (New York City). The outbreak was characterized by a high attack rate (78 per cent overall); the predominant symptoms were myalgias, chills, fatigue, fever, and headache. There was a clustering of cases in an office that was air cooled by a dedicated cooling tower separate from the remainder of the building. A high concentration of live L. Pneumophila cells in the cooling tower was quantified. Airborne spread via settle plates placed along the air intake system and within the office was demonstrated. Legionella pneumophila serogroup 1 antigen was found in the urine of two cases, and identical monoclonal antibody reactivity patterns of isolates from all sources was observed. Difficulty was experienced in eliminating the organism from the tower.
摘要
1984年4月下旬，在曼哈顿下城（纽约市）的一座办公楼里对一场庞蒂亚克热疫情进行了调查。此次疫情的特点是发病率很高（总体发病率为78%）；主要症状为肌痛、寒战、疲劳、发热和头痛。在一间由与大楼其余部分分开的专用冷却塔进行空气冷却的办公室里病例集中出现。对冷却塔中高浓度的嗜肺军团菌活细胞进行了定量分析。通过沿进气系统放置在办公室内的沉降平板证实了空气传播。在两例病例的尿液中发现了嗜肺军团菌血清群1抗原，并且观察到来自所有来源的分离株具有相同的单克隆抗体反应模式。在从冷却塔中清除该病原体方面遇到了困难。
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