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基于深度学习的计算机断层扫描图像特征对非腹膜结直肠癌的诊断。

Diagnosis of Nonperitonealized Colorectal Cancer with Computerized Tomography Image Features under Deep Learning.

机构信息

Department of Critical Care Medicine, The Second Affiliated Hospital of Shaanxi University of Chinese Medicine, Xianyang 712000, Shaanxi, China.

Image Center, The Second Affiliated Hospital of Shaanxi University of Chinese Medicine, Xianyang 712000, Shaanxi, China.

出版信息

Contrast Media Mol Imaging. 2022 May 25;2022:1886406. doi: 10.1155/2022/1886406. eCollection 2022.

Abstract

This study aimed to explore the value of abdominal computerized tomography (CT) three-dimensional reconstruction using the dense residual single-axis super-resolution algorithm in the diagnosis of nonperitonealized colorectal cancer (CC). 103 patients with nonperitonealized CC (the lesion was located in the ascending colon or descending colon) were taken as the research subjects. The imagological tumor (T) staging, the extramural depth (EMD) of the cancer tissues, and the extramural vascular invasion (EMVI) grading were analyzed. A dense residual single-axis super-resolution network model was also constructed for enhancing CT images. It was found that the CT images processed using the algorithm were clear, and the peak signal-to-noise ratio (PSNR) and structural similarity (SSIM) were 33.828 dB and 0.856, respectively. In the imagological T staging of CC patients, there were 17 cases in the T3 stage and 68 cases in the T4 stage. With the EMD increasing, the preoperative carcinoembryonic antigen (CEA) highly increased, and the difference was statistically significant ( < 0.05). The postoperative hospital stays of patients were also different with different grades of EMVI. The hospital stay of grade 1 patients (19.45 days) was much longer than that of grade 2 patients (13.19 days), grade 3 patients (15.36 days), and grade 4 patients (14.36 days); the differences were of statistical significance ( < 0.05). It was suggested that CT images under the deep learning algorithm had a high clinical value in the evaluation of T staging, EMD, and EMVI for the diagnosis of CC.

摘要

本研究旨在探讨基于密集残差单轴超分辨率算法的腹部计算机断层扫描(CT)三维重建在诊断非腹膜化结直肠癌(CC)中的价值。选取 103 例非腹膜化 CC 患者(病变位于升结肠或降结肠)作为研究对象。分析影像学肿瘤(T)分期、癌组织的外膜深度(EMD)和外膜血管侵犯(EMVI)分级,并构建密集残差单轴超分辨率网络模型增强 CT 图像。结果发现,算法处理后的 CT 图像清晰,峰值信噪比(PSNR)和结构相似性(SSIM)分别为 33.828dB 和 0.856。在 CC 患者的 CT 影像学 T 分期中,T3 期 17 例,T4 期 68 例。随着 EMD 的增加,术前癌胚抗原(CEA)明显升高,差异有统计学意义( < 0.05)。不同 EMVI 分级患者的术后住院时间也不同。1 级患者(19.45 天)的住院时间明显长于 2 级患者(13.19 天)、3 级患者(15.36 天)和 4 级患者(14.36 天),差异有统计学意义( < 0.05)。提示深度学习算法下的 CT 图像对 CC 的 T 分期、EMD 和 EMVI 评估具有较高的临床价值。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2df1/9159838/117f3a699718/CMMI2022-1886406.006.jpg

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