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用于治疗不同程度骨关节炎的水凝胶

Hydrogels for Treatment of Different Degrees of Osteoarthritis.

作者信息

Wang Shuze, Qiu Yueyang, Qu Liu, Wang Qiang, Zhou Qing

机构信息

School and Hospital of Stomatology, China Medical University, Shenyang, China.

Liaoning Provincial Key Laboratory of Oral Diseases, Shenyang, China.

出版信息

Front Bioeng Biotechnol. 2022 Jun 6;10:858656. doi: 10.3389/fbioe.2022.858656. eCollection 2022.

Abstract

Osteoarthritis (OA) is a common disease that severely restricts human activities and degrades the quality of life. Every year, millions of people worldwide are diagnosed with osteoarthritis, placing a heavy burden on society. Hydrogels, a polymeric material with good biocompatibility and biodegradability, are a novel approach for the treatment of osteoarthritis. In recent years, this approach has been widely studied with the development of materials science and tissue engineering technology. We reviewed the research progress of hydrogels in the treatment of osteoarthritis in the past 3 years. We summarized the required hydrogel properties and current applications according to the development and treatment of osteoarthritis. Furthermore, we listed the challenges of hydrogels for different types of osteoarthritis and presented prospects for future development.

摘要

骨关节炎(OA)是一种严重限制人类活动并降低生活质量的常见疾病。每年,全球数百万人被诊断出患有骨关节炎,给社会带来沉重负担。水凝胶是一种具有良好生物相容性和生物降解性的聚合材料,是治疗骨关节炎的一种新方法。近年来,随着材料科学和组织工程技术的发展,这种方法得到了广泛研究。我们回顾了过去3年水凝胶在骨关节炎治疗方面的研究进展。我们根据骨关节炎的发展和治疗总结了所需的水凝胶特性及当前应用。此外,我们列出了水凝胶在不同类型骨关节炎治疗中面临的挑战,并展望了未来的发展前景。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ae69/9207401/437c90b7cbc2/fbioe-10-858656-g001.jpg

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