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溃疡性结肠炎的营养与补充。

Nutrition and Supplementation in Ulcerative Colitis.

机构信息

Department of Dietetics and Clinical Nutrition, Medical University of Bialystok, Ul. Mieszka I 4B, 15-054 Bialystok, Poland.

出版信息

Nutrients. 2022 Jun 14;14(12):2469. doi: 10.3390/nu14122469.

Abstract

Ulcerative colitis (UC) belongs to the group of inflammatory bowel diseases (IBD). UC is an incurable, diffuse, and chronic inflammatory process of the colonic mucosa with alternating periods of exacerbation and remission. This review aimed to analyze the scientific research conducted to date to determine what impact different nutritional plans and dietary supplements may have on the course of UC. The latest 98 articles about nutrition and supplementation in ulcerative colitis were used to prepare the work. Certain components in food can greatly influence the course of UC, inducing changes in the composition and function of the gut microbiome. This activity may be an important part of therapy for people with IBD. The Mediterranean diet has shown the most promising results in the treatment of patients with UC due to its high content of biologically active foods. Patients with UC may benefit from the UC Exclusion Diet (UCED); however, it is a new nutritional plan that requires further research. Patents frequently resort to unconventional diets, which, because of their frequent elimination of nutrient-rich foods, can worsen the health and nutritional status of those who follow them. The benefits of omega-3 fatty acids and probiotics supplementation may have additional therapeutic effects; however, the evidence is not unequivocal.

摘要

溃疡性结肠炎(UC)属于炎症性肠病(IBD)的范畴。UC 是一种无法治愈的、弥漫性的、慢性的结肠黏膜炎症过程,其特点是反复发作和缓解交替。本综述旨在分析迄今为止进行的科学研究,以确定不同的营养计划和膳食补充剂对 UC 病程可能产生的影响。该工作使用了最新的 98 篇关于溃疡性结肠炎营养和补充剂的文章。食物中的某些成分可以极大地影响 UC 的病程,诱导肠道微生物群的组成和功能发生变化。这种活动可能是 IBD 患者治疗的重要组成部分。由于富含生物活性物质,地中海饮食在 UC 患者的治疗中显示出最有前途的结果。UC 患者可能受益于 UC 排除饮食(UCED);然而,这是一种新的营养计划,需要进一步研究。患者经常采用非传统饮食,由于频繁排除富含营养的食物,这可能会使遵循这些饮食的人的健康和营养状况恶化。ω-3 脂肪酸和益生菌补充剂的益处可能具有额外的治疗效果;然而,证据并不明确。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4938/9231317/a50a7856c74d/nutrients-14-02469-g001.jpg

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