Ide Mark, Karimova Malika, Setterfield Jane
Centre for Host-Microbiome Interactions, Faculty of Dentistry, Oral and Craniofacial Sciences, King's College London, London, United Kingdom.
Front Oral Health. 2022 Jun 7;3:866695. doi: 10.3389/froh.2022.866695. eCollection 2022.
Periodontal and chronic oral mucosal diseases are significant life impacting conditions which may co-exist and synergistically act to cause more severe and widespread oral pathology with enhanced challenges in effective management. Clinicians regularly observe these effects and struggle to effectively manage both problems in many patients. There is limited understanding of many basic and applied scientific elements underpinning potentially shared aetiopathological features and management. Recent developments in translational science provide an opportunity to greater improve knowledge and subsequently care for patients with these problems.
牙周病和慢性口腔黏膜病是严重影响生活的疾病,它们可能同时存在并协同作用,导致更严重、更广泛的口腔病变,给有效治疗带来更大挑战。临床医生经常观察到这些影响,并在许多患者中努力有效治疗这两个问题。对于许多潜在共同的病因病理特征和治疗方法的基础科学元素,人们的了解有限。转化医学的最新进展为更好地提高认识并进而治疗这些疾病患者提供了机会。