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生长于摩洛哥野外的[具体植物名称1]和[具体植物名称2]的抗氧化、抗糖尿病和抗菌潜力及化学成分

Antioxidant, Antidiabetic, and Antibacterial Potentials and Chemical Composition of and Grown Wild in Morocco.

作者信息

Al-Mijalli Samiah Hamad, Assaggaf Hamza, Qasem Ahmed, El-Shemi Adel G, Abdallah Emad M, Mrabti Hanae Naceiri, Bouyahya Abdelhakim

机构信息

Department of Biology, College of Sciences, Princess Nourah Bint Abdulrahman University, P.O. Box 84428, Riyadh 11671, Saudi Arabia.

Laboratory Medicine Department, Faculty of Applied Medical Sciences, Umm Al-Qura University, Makkah 21955, Saudi Arabia.

出版信息

Adv Pharmacol Pharm Sci. 2022 Jun 15;2022:2844880. doi: 10.1155/2022/2844880. eCollection 2022.

Abstract

This work evaluated in vitro antioxidant, antidiabetic, and antibacterial properties of (. ) and (. ) essential oils (EO). The EOs were extracted, and their chemical composition was determined using GC-MS analysis. The in vitro antioxidant, antidiabetic, and antibacterial activities of . and . EO were shown to be remarkable. Furthermore, . EO demonstrated better antioxidant findings (using DPPH, ABTS, and FRAP test) than . EO ( < 0.5). There were no significant differences in the inhibitory effects of the EOs on -amylase and -glucosidase activities in the antidiabetic assays. All of the examined bacterial strains (10 different strains), with the exception of . , demonstrated significant sensitivity to the tested EOs, with . EO exhibiting better activity than . EO. Thus, the research indicated that EO from these two medicinal plants has considerable potential for application in the formulation of antibacterial, antioxidant, and antidiabetic pharmaceuticals. However, more research studies are required to interpret the pharmacologic action of the studied EOs and their principal constituents and to confirm their safety.

摘要

本研究评估了[植物名称1]([植物拉丁名1])和[植物名称2]([植物拉丁名2])精油(EO)的体外抗氧化、抗糖尿病和抗菌特性。提取了这些精油,并使用气相色谱 - 质谱(GC - MS)分析确定其化学成分。结果表明,[植物名称1]和[植物名称2]精油的体外抗氧化、抗糖尿病和抗菌活性显著。此外,[植物名称1]精油在抗氧化测试(使用DPPH、ABTS和FRAP法)中表现出比[植物名称2]精油更好的结果(P < 0.5)。在抗糖尿病实验中,两种精油对α - 淀粉酶和α - 葡萄糖苷酶活性的抑制作用没有显著差异。除[细菌名称]外,所有检测的细菌菌株(10种不同菌株)对测试的精油均表现出显著敏感性,其中[植物名称1]精油的活性优于[植物名称2]精油。因此,该研究表明,这两种药用植物的精油在抗菌、抗氧化和抗糖尿病药物制剂中具有相当大的应用潜力。然而,需要更多的研究来解释所研究精油及其主要成分的药理作用,并确认其安全性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7b54/9217590/fa0447cf2063/APS2022-2844880.001.jpg

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