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[突尼斯野外犬只中抗狂犬病疫苗效力的血清学评估]

[Serological evaluation of the efficacy of an antirabies vaccine in field dogs in Tunisia].

作者信息

Haddad N

出版信息

Ann Rech Vet. 1987;18(1):63-7.

PMID:3579184
Abstract

We have vaccinated with an inactivated experimental vaccine, Rabi Rabta, prepared in lamb brain 52 dogs from the field in Tunisia and we tested by recommended serological methods the production of specific antibodies. The animals (35) received a boost injection after one year and the control of the immunological response was done on the same way after one month. This work done on 27 dogs showed very low serological data. A comparable batch of 42 dogs was immunised with a commercial vaccine with the same procedure; the results obtained from 17 dogs were not very different. This is apparently in contradiction with the success obtained by the National Program against Rabies launched in Tunisia since 1982.

摘要

我们用在羊脑制备的灭活实验性疫苗“拉比·拉布塔”对来自突尼斯野外的52只狗进行了接种,并通过推荐的血清学方法检测了特异性抗体的产生。其中35只动物在一年后接受了加强注射,并在一个月后以同样的方式进行免疫反应监测。对27只狗进行的这项研究显示血清学数据非常低。用相同程序对42只狗接种了一批商业疫苗;从17只狗获得的结果没有太大差异。这显然与突尼斯自1982年启动的国家狂犬病防治计划所取得的成功相矛盾。

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