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基于优化去卷积算法的 CT 灌注成像在急性脑梗死诊断中的应用。

Optimized Deconvolutional Algorithm-based CT Perfusion Imaging in Diagnosis of Acute Cerebral Infarction.

机构信息

Department of Radiology, the Third Medical Centre, Chinese PLA General Hospital, Beijing 100039, China.

Department of Geriatric, the Third Medical Centre, Chinese PLA General Hospital, Beijing 100039, China.

出版信息

Contrast Media Mol Imaging. 2022 Jun 6;2022:8728468. doi: 10.1155/2022/8728468. eCollection 2022.

DOI:10.1155/2022/8728468
PMID:35800236
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9192278/
Abstract

To apply deconvolution algorithm in computer tomography (CT) perfusion imaging of acute cerebral infarction (ACI), a convolutional neural network (CNN) algorithm was optimized first. RIU-Net was applied to segment CT image, and then equipped with SE module to enhance the feature extraction ability. Next, the BM3D algorithm, Dn CNN, and Cascaded CNN were compared for denoising effects. 80 patients with ACI were recruited and grouped for a retrospective analysis. The control group utilized the ordinary method, and the observation group utilized the algorithm proposed. The optimized model was utilized to extract the feature information of the patient's CT images. The results showed that after the SE module pooling was added to the RIU-Net network, the utilization rate of the key features was raised. The specificity of patients in observation group was 98.7%, the accuracy was 93.7%, and the detected number was (1.6 ± 0.2). The specificity of patients in the control group was 93.2%, the accuracy was 87.6%, and the detected number was (1.3 ± 0.4). Obviously, the observation group was superior to the control group in all respects (  0.05). In conclusion, the optimized model demonstrates superb capabilities in image denoising and image segmentation. It can accurately extract the information to diagnose ACI, which is suggested clinically.

摘要

为了在急性脑梗死(ACI)的计算机断层扫描(CT)灌注成像中应用去卷积算法,首先优化了卷积神经网络(CNN)算法。应用 RIU-Net 对 CT 图像进行分割,然后配备 SE 模块增强特征提取能力。接着,比较了 BM3D 算法、DnCNN 和级联 CNN 的去噪效果。纳入 80 例 ACI 患者进行回顾性分析。对照组采用常规方法,观察组采用提出的算法。优化模型用于提取患者 CT 图像的特征信息。结果表明,在 RIU-Net 网络中添加 SE 模块池化后,关键特征的利用率提高。观察组患者的特异性为 98.7%,准确性为 93.7%,检出数为(1.6±0.2)。对照组患者的特异性为 93.2%,准确性为 87.6%,检出数为(1.3±0.4)。观察组在各方面均明显优于对照组(  0.05)。结论:优化模型在图像去噪和图像分割方面表现出卓越的性能。它可以准确提取用于诊断 ACI 的信息,这在临床上是有建议意义的。

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