Escola Superior de Biotecnologia, Universidade Católica Portuguesa, Rua Diogo Botelho 1327, 4169-005, Porto, Portugal.
Amyris Bio Products Portugal Unipessoal Lda, Rua Diogo Botelho 1327, 4169-005, Porto, Portugal.
Microb Ecol. 2023 Jul;86(1):86-96. doi: 10.1007/s00248-022-02070-0. Epub 2022 Jul 9.
Skin harbors an important microbial ecosystem - the skin microbiota that is in homeostasis with its host and is beneficial for human health. Cosmetic products have the potential to interfere with this microbial community; therefore their impact should be assessed. The aim of this review is to highlight the importance of skin microbiota in the cosmetic industry. Several studies determined that cosmetic ingredients have the potential to disrupt the skin microbiota equilibrium leading to the development of skin diseases and dysregulation of immune response. These studies led their investigation by using different methodologies and models, concluding that methods must be chosen according to the aim of the study, the skin site to be evaluated, and the target population of the cosmetics. Overall, it is crucial to test the impact of cosmetics in the skin microbiota and to stablish standard procedures, as well as specific criteria that allow to classify a cosmetic product as skin microbiota friendly.
皮肤拥有一个重要的微生物生态系统——皮肤微生物群，它与宿主处于平衡状态，对人类健康有益。化妆品有可能会干扰这个微生物群落；因此，应该对其影响进行评估。本综述的目的是强调皮肤微生物群在化妆品行业中的重要性。多项研究表明，化妆品成分有可能破坏皮肤微生物群的平衡，导致皮肤疾病的发展和免疫反应失调。这些研究使用不同的方法和模型进行了调查，得出的结论是，必须根据研究目的、要评估的皮肤部位以及化妆品的目标人群来选择方法。总的来说，测试化妆品对皮肤微生物群的影响并建立标准程序以及允许将化妆品产品分类为对皮肤微生物群友好的具体标准非常重要。
