Wu You, Guo Xiaofeng, Peng Yuliang, Fang Zongping, Zhang Xijing
Department of Intensive Care Unit, Xijing Hospital, The Fourth Military Medical University, Xi'an, China.
Department of Intensive Care Unit, Joint Logistics Force No. 988 Hospital, Zhengzhou, China.
Front Physiol. 2022 Jun 29;13:879430. doi: 10.3389/fphys.2022.879430. eCollection 2022.
Physical exercise is a planned, purposeful action to keep a healthy lifestyle and improve physical fitness. Physical exercise has been widely used as a non-pharmacological approach to preventing and improving a wide range of diseases, including cardiovascular disease, cancer, metabolic disease, and neurodegenerative disease. However, the effects of physical exercise on sepsis have not been summarized until now. In this review, we discuss the effects of physical exercise on multiple organ functions and the short- and long-time outcomes of sepsis. Furthermore, the molecular mechanisms underlying the protective effects of physical exercise on sepsis are discussed. In conclusion, we consider that physical exercise may be a beneficial and non-pharmacological alternative for the treatment of sepsis.
体育锻炼是一种有计划、有目的的行为，旨在保持健康的生活方式并提高身体素质。体育锻炼已被广泛用作一种非药物方法来预防和改善多种疾病，包括心血管疾病、癌症、代谢性疾病和神经退行性疾病。然而，迄今为止，体育锻炼对脓毒症的影响尚未得到总结。在本综述中，我们讨论了体育锻炼对多器官功能以及脓毒症短期和长期预后的影响。此外，还讨论了体育锻炼对脓毒症保护作用的潜在分子机制。总之，我们认为体育锻炼可能是治疗脓毒症的一种有益的非药物替代方法。
