优化从万寿菊花瓣中提取多酚及其在葵花籽油中的应用：抗癌和抗氧化性能。
Optimized Green Extraction of Polyphenols from L. Petals for Their Application in Sunflower Oil: Anticancer and Antioxidant Properties.
机构信息
School of Food and Biological Engineering, Jiangsu University, Zhenjiang 212013, China.
Food Science Department, Faculty of Agriculture, Cairo University, Giza 12613, Egypt.
出版信息
Molecules. 2022 Jul 6;27(14):4329. doi: 10.3390/molecules27144329.
The total phenolic content (TPC) from L. petals were extracted using ethanolic solvent extraction at concentrations ranging from 0 to 90% and an SCF-CO co-solvent at various pressures. Ultrasound-assisted extraction parameters were optimized using response surface methodology (RSM). Antioxidant and anticancer properties of total phenols were assessed. An SCF-CO co-solvent extract was nano-encapsulated and applied to sunflower oil without the addition of an antioxidant. The results indicated that the best treatment for retaining TPC and total flavonoids content (TFC) was SCF-CO co-solvent followed by the ultrasound and ethanolic extraction procedures. Additionally, the best antioxidant activity by β-carotene/linoleic acid and DPPH free radical-scavenging test systems was observed by SCF-CO co-solvent then ultrasound and ethanolic extraction methods. SCF-CO co-solvent recorded the highest inhibition % for PC3 (76.20%) and MCF7 (98.70%) and the lowest IC value for PC3 (145 µ/mL) and MCF7 (96 µ/mL). It was discovered that fortifying sunflower oil with SCF-CO co-solvent nanoparticles had a beneficial effect on free fatty acids and peroxide levels. The SCF-CO method was finally found to be superior and could be used in large-scale processing.
采用不同浓度的乙醇溶剂和超临界 CO2 共溶剂，在不同压力下对百合花瓣中的总酚含量（TPC）进行提取。采用响应面法优化超声辅助提取参数。评估总酚的抗氧化和抗癌特性。将超临界 CO2 共溶剂提取物进行纳米封装，并应用于葵花籽油中，无需添加抗氧化剂。结果表明，保留 TPC 和总黄酮含量（TFC）的最佳处理方法是超临界 CO2 共溶剂，其次是超声和乙醇提取方法。此外，通过β-胡萝卜素/亚油酸和 DPPH 自由基清除试验系统观察到超临界 CO2 共溶剂的最佳抗氧化活性，然后是超声和乙醇提取方法。超临界 CO2 共溶剂对 PC3（76.20%）和 MCF7（98.70%）的抑制率最高，对 PC3（145 µ/mL）和 MCF7（96 µ/mL）的 IC 值最低。结果表明，用超临界 CO2 共溶剂纳米粒子强化葵花籽油对游离脂肪酸和过氧化物水平有有益的影响。最终发现超临界 CO2 方法更优越，可用于大规模加工。
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