利用超分子组装对抗抗生素耐药性
Combatting Antibiotic Resistance Using Supramolecular Assemblies.
作者信息
Guo Shuwen, He Yuling, Zhu Yuanyuan, Tang Yanli, Yu Bingran
机构信息
Key Laboratory of Analytical Chemistry for Life Science of Shaanxi Province, School of Chemistry and Chemical Engineering, Shaanxi Normal University, Xi'an 710100, China.
Institute of Basic and Translational Medicine, Xi'an Medical University, No. 1 Xinwang Road, Xi'an 710021, China.
出版信息
Pharmaceuticals (Basel). 2022 Jun 28;15(7):804. doi: 10.3390/ph15070804.
Antibiotic resistance has posed a great threat to human health. The emergence of antibiotic resistance has always outpaced the development of new antibiotics, and the investment in the development of new antibiotics is diminishing. Supramolecular self-assembly of the conventional antibacterial agents has been proved to be a promising and versatile strategy to tackle the serious problem of antibiotic resistance. In this review, the recent development of antibacterial agents based on supramolecular self-assembly strategies will be introduced.
抗生素耐药性已对人类健康构成巨大威胁。抗生素耐药性的出现始终快于新型抗生素的研发，且新型抗生素研发的投入正在减少。传统抗菌剂的超分子自组装已被证明是应对严重抗生素耐药性问题的一种有前景且通用的策略。在本综述中，将介绍基于超分子自组装策略的抗菌剂的最新进展。
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