Cao Fang, Zhao Xupeng, Lv Xiaoqing, Hu Liangchen, Jiang Wenhui, Yang Feng, Chi Li, Chang Pengying, Xu Chen, Xie Yiyang
Key Laboratory of Optoelectronics Technology, Ministry of Education, Beijing University of Technology, Beijing 100124, China.
State Key Laboratory of Integrated Optoelectronics, Institute of Semiconductor, Chinese Academy of Sciences, Beijing 100083, China.
Nanomaterials (Basel). 2022 Jul 29;12(15):2607. doi: 10.3390/nano12152607.
The work introduces a localized surface plasmon resonance (LSPR) sensor chip integrated with vertical-cavity surface-emitting lasers (VCSELs). Using VCSEL as the light source, the hexagonal gold nanoparticle array was integrated with anodic aluminum oxide (AAO) as the mask on the light-emitting end face. The sensitivity sensing test of the refractive index solution was realized, combined with microfluidic technology. At the same time, the finite-difference time- domain (FDTD) algorithm was applied to model and simulate the gold nanostructures. The experimental results showed that the output power of the sensor was related to the refractive index of the sucrose solution. The maximum sensitivity of the sensor was 1.65 × 10 nW/RIU, which gives it great application potential in the field of biomolecular detection.
这项工作介绍了一种集成了垂直腔面发射激光器（VCSEL）的局域表面等离子体共振（LSPR）传感器芯片。以VCSEL作为光源，在发光端面上将六边形金纳米颗粒阵列与阳极氧化铝（AAO）作为掩膜集成在一起。结合微流控技术实现了对折射率溶液的灵敏度传感测试。同时，应用时域有限差分（FDTD）算法对金纳米结构进行建模和模拟。实验结果表明，该传感器的输出功率与蔗糖溶液的折射率有关。该传感器的最大灵敏度为1.65×10 nW/RIU，这使其在生物分子检测领域具有巨大的应用潜力。
