Neuropsychological Evaluation and Rehabilitation Center (CERNEP), University of Almeria, Carretera de Sacramento, s / n. La Cañada de San Urbano. 04120, Almeria, Spain.
Department of Psychology, University of Almeria Spain, Carretera de Sacramento, s /n. La Cañada de San Urbano. 04120, Almeria, Spain.
Cogn Res Princ Implic. 2022 Aug 12;7(1):78. doi: 10.1186/s41235-022-00428-z.
Positive symptoms of schizophrenia are associated with significant difficulties in daily functioning, and these difficulties have been associated with impaired executive functions (EEFF). However, specific cognitive and socio-emotional executive deficits have not been fully established.
The present study has several objectives. First, we aimed to examine the specific deficits in cognitive and socio-emotional EEFF in a group of patients with schizophrenia with a predominance of positive symptoms, as well as to determine if these patients present clinically significant scores in any of the three fronto-subcortical behavioral syndromes: Dorsolateral, Orbitofrontal, or Anterior Cingulate.
The sample consisted of 54 patients, 27 with a predominance of positive symptoms, and 27 healthy controls matched for gender, age, and education. The two groups completed four cognitive and three socio-emotional EEFF tasks. In the group of patients, positive symptoms were evaluated using the scale for the Evaluation of Positive Symptoms (SANS), while the behavioral alterations associated with the three fronto-subcortical syndromes were evaluated using the Frontal System Behavior Scale (FrSBe).
The patients, in comparison with a control group, presented specific deficits in cognitive and socio-emotional EEFF. In addition, a high percentage of patients presented clinically significant scores on the three fronto-subcortical syndromes.
The affectation that these patients present, in terms of both cognitive and emotional components, highlights the importance of developing a neuropsychological EEFF intervention that promotes the recovery of the affected cognitive capacities and improves the social and emotional functioning of the affected patients.
精神分裂症的阳性症状与日常生活功能的严重障碍有关，而这些障碍与执行功能障碍（EEFF）有关。然而，特定的认知和社会情感执行缺陷尚未完全确定。
本研究有几个目的。首先，我们旨在检查一组以阳性症状为主的精神分裂症患者的认知和社会情感 EEFF 特定缺陷，并确定这些患者是否在三个额皮质下行为综合征中的任何一个中表现出临床显著的分数：背外侧、眶额或前扣带。
该样本包括 54 名患者，其中 27 名患者以阳性症状为主，27 名健康对照组匹配性别、年龄和教育。两组均完成了四项认知和三项社会情感 EEFF 任务。在患者组中，使用阳性症状评估量表（SANS）评估阳性症状，而使用额叶系统行为量表（FrSBe）评估与三个额皮质下综合征相关的行为改变。
与对照组相比，患者在认知和社会情感 EEFF 方面表现出特定的缺陷。此外，有很高比例的患者在三个额皮质下综合征上表现出临床显著的分数。
这些患者在认知和情感成分方面的表现突出了发展神经心理学 EEFF 干预的重要性，该干预可以促进受影响的认知能力的恢复，并改善受影响患者的社会和情感功能。
