来自山梨叶珍珠菜的新型色酮类化合物。

Novel chromones from Spathelia sorbifolia.

作者信息

Suwanborirux K, Chang C J, Cassady J M

出版信息

J Nat Prod. 1987 Jan-Feb;50(1):102-7. doi: 10.1021/np50049a014.

Abstract

Three new chromones, namely 10-(2',3'-dihydroxy-3'-methylbutanyl)-spatheliachromen, 10-(1',2',3'-trihydroxy-3'-methylbutanyl)spatheliachromen, and 6-(3'-hydroxy-3'-methyl-trans-but-1'-enyl)-O-methylisospatheliachrome n were isolated from the 10% aqueous MeOH extract of the twigs and leaves of Spathelia sorbifolia, together with five known chromones. Compound 2, the known spatheliabischromen, and 5-O-methylsorbifolin showed cytotoxicity against 9PS cells in culture.

摘要

从山梨叶白鹃梅（Spathelia sorbifolia）嫩枝和叶片的10%甲醇水溶液提取物中分离出三种新的色酮，即10-(2',3'-二羟基-3'-甲基丁基)-匙叶白鹃梅色原酮、10-(1',2',3'-三羟基-3'-甲基丁基)匙叶白鹃梅色原酮和6-(3'-羟基-3'-甲基反式-丁-1'-烯基)-O-甲基异匙叶白鹃梅色原酮，同时还分离出五种已知色酮。化合物2，即已知的匙叶双色酮，以及5-O-甲基山梨醇苷在体外培养中对9PS细胞显示出细胞毒性。