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电化学测定生物体液、药物制剂、环境资源和食品中抗生素环丙沙星的最新趋势:直接和间接方法。

Recent trends on electrochemical determination of antibiotic Ciprofloxacin in biological fluids, pharmaceutical formulations, environmental resources and foodstuffs: Direct and indirect approaches.

机构信息

Sultan Moulay Slimane University of Beni Mellal, Laboratory of Materials Science, Mathematics and Environment, Polydisciplinary Faculty, 25 000, Khouribga, Morocco.

Sultan Moulay Slimane University of Beni Mellal, Laboratory of Materials Science, Mathematics and Environment, Polydisciplinary Faculty, 25 000, Khouribga, Morocco; Sidi Mohamed Ben Abdellah University, Engineering Laboratory of Organometallic, Molecular Materials, and Environment, Faculty of Sciences, Fez, Morocco.

出版信息

Food Chem Toxicol. 2022 Oct;168:113378. doi: 10.1016/j.fct.2022.113378. Epub 2022 Aug 18.

DOI:10.1016/j.fct.2022.113378
PMID:35987282
Abstract

In the last few decades, pharmaceuticals, credited with saving millions of lives, have emerged as a new class of environmental contaminants. These compounds can have both chronic and acute harmful effects on aquatic ecosystems and consequently on human health. Therefore, there is an urgent need for the development of extremely sensitive, portable, and low-cost devices to perform analysis. In the present review article, recent reports on the application of various voltammetric and photo-electrochemical techniques using different electrode materials for the determination of antibiotic Ciprofloxacin (CIPRO) are reported. This review provides an insight into direct and indirect electrochemical approaches as well as the photoelectrochemical methods used for the determination of CIPRO. Emphasis is put on the applications of unmodified and modified carbon-based electrodes considering the modifier, supporting electrolytes, analytical method, concentration range, limit of detection, and real matrices. Carbon-based electrodes are the most used materials attributed to their commercial availability, reduced cost, high chemical stability, and non-toxicity.

摘要

在过去的几十年中,药品作为一类新型的环境污染物,被认为拯救了数百万人的生命。这些化合物会对水生生态系统以及人类健康产生慢性和急性的有害影响。因此,迫切需要开发超灵敏、便携和低成本的设备来进行分析。在本文综述中,报告了使用不同电极材料的各种伏安法和光电化学技术在测定抗生素环丙沙星(CIPRO)方面的最新应用。本综述深入探讨了直接和间接电化学方法以及光电化学方法在测定 CIPRO 方面的应用。重点介绍了未修饰和修饰的基于碳的电极的应用,考虑了修饰剂、支持电解质、分析方法、浓度范围、检测限和实际基质。基于碳的电极是最常用的材料,因为它们具有商业可用性、低成本、高化学稳定性和无毒的特点。

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