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银屑病伴发间质性肺疾病

Concomitant Interstitial Lung Disease With Psoriasis.

作者信息

Kharibam Prabin, Laishram Sushma, Choudhary Nikita, Choudhury Arnab, Kant Ravi

机构信息

Department of Internal Medicine, All India Institute of Medical Sciences Rishikesh, Rishikesh, IND.

Department of Dermatology, Venereology, and Leprosy, All India Institute of Medical Sciences Rishikesh, Rishikesh, IND.

出版信息

Cureus. 2022 Jul 18;14(7):e26979. doi: 10.7759/cureus.26979. eCollection 2022 Jul.

Abstract

Interstitial lung disease is occasionally reported in patients with psoriasis as drug-induced pneumonitis secondary to concomitant use of immunosuppressants in most cases. Although few cases have been reported describing the simultaneous existence of psoriasis and interstitial pneumonia, there are no reports that clearly show their direct association. A 55-year-old male known case of psoriasis and hypertension presented to the emergency department with complaints of pain and weakness of bilateral upper limbs following an episode of seizure and shortness of breath on exertion for one year. Following workup, the patient was diagnosed to have interstitial lung disease. There was no history of any immunosuppressant or use of biologics. So, immune dysfunction triggered by psoriasis might have caused the lung fibrotic changes. Careful monitoring of lung and skin lesions is vital for diagnosing psoriasis-associated pneumonia.

摘要

在大多数情况下,银屑病患者偶尔会报告出现间质性肺病,这是继发于同时使用免疫抑制剂的药物性肺炎。虽然有少数病例报告描述了银屑病和间质性肺炎同时存在,但尚无报告明确显示它们之间的直接关联。一名55岁男性,已知患有银屑病和高血压,因癫痫发作后双侧上肢疼痛和无力以及一年来劳力性呼吸急促而到急诊科就诊。经过检查,该患者被诊断为间质性肺病。没有任何免疫抑制剂或生物制剂使用史。因此,银屑病引发的免疫功能障碍可能导致了肺部纤维化改变。仔细监测肺部和皮肤病变对于诊断银屑病相关肺炎至关重要。

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