Matulevičiūtė Indrė, Sidaraitė Agnė, Tatarūnas Vacis, Veikutienė Audronė, Dobilienė Olivija, Žaliūnienė Dalia
Department of Ophthalmology, Lithuanian University of Health Sciences, 44307 Kaunas, Lithuania.
Institute of Cardiology, Lithuanian University of Health Sciences, 44307 Kaunas, Lithuania.
Diagnostics (Basel). 2022 Aug 20;12(8):2016. doi: 10.3390/diagnostics12082016.
. Optical coherence tomography (OCT) and optical coherence tomography angiography (OCTA) allowed visualization of retina and choroid to nearly the capillary level; however, the relationship between systemic macrovascular status and retinal microvascular changes is not yet known well. . Our purpose was to assess the impact of retinal optical coherence tomography (OCT) and optical coherence tomography angiography (OCTA) parameters on prediction of coronary heart disease (CHD) in acute myocardial infarction (MI) and chronic three vessel disease (3VD) groups. . This observational study included 184 patients-26 in 3VD, 76 in MI and 82 in healthy participants groups. Radial scans of the macula and OCTA scans of the central macula (superficial (SCP) and deep (DCP) capillary plexuses) were performed on all participants. All participants underwent coronary angiography. . Patients in MI groups showed decreased parafoveal total retinal thickness as well as GCL+ retinal thickness. Outer circle total retinal thickness and GCL+ retinal thickness were lowest in the 3VD group. The MI group had thinner, while 3VD the thinnest, choroid. A decrease in choroidal thickness and vascular density could predict 3VD. . A decrease in retinal and choroidal thickness as well as decreased vascular density in the central retinal region may predict coronary artery disease. OCT and OCTA could be a significant, safe, and noninvasive tool for the prediction of coronary artery disease.
光学相干断层扫描（OCT）和光学相干断层扫描血管造影（OCTA）能够将视网膜和脉络膜可视化至近乎毛细血管水平；然而，全身大血管状态与视网膜微血管变化之间的关系尚不清楚。我们的目的是评估视网膜光学相干断层扫描（OCT）和光学相干断层扫描血管造影（OCTA）参数对急性心肌梗死（MI）和慢性三支血管病变（3VD）组冠心病（CHD）预测的影响。这项观察性研究纳入了184例患者——3VD组26例、MI组76例和健康参与者组82例。对所有参与者进行黄斑区的径向扫描以及黄斑中心的OCTA扫描（浅层（SCP）和深层（DCP）毛细血管丛）。所有参与者均接受了冠状动脉造影。MI组患者的黄斑旁视网膜总厚度以及神经节细胞层+视网膜厚度降低。3VD组的外环视网膜总厚度和神经节细胞层+视网膜厚度最低。MI组脉络膜较薄，而3VD组脉络膜最薄。脉络膜厚度和血管密度降低可预测3VD。视网膜和脉络膜厚度降低以及视网膜中央区域血管密度降低可能预测冠状动脉疾病。OCT和OCTA可能是预测冠状动脉疾病的一种重要、安全且无创的工具。
