Department of Clinical Immunology, Medical University of Warsaw, Nowogrodzka 59, 02-006 Warsaw, Poland.
Department of Drug Technology and Pharmaceutical Biotechnology, Medical University of Warsaw, Banacha 1, 02-097 Warsaw, Poland.
Int J Mol Sci. 2022 Aug 11;23(16):8980. doi: 10.3390/ijms23168980.
(Berk.) Pegler, also known as shiitake mushroom, is a popular edible macrofungus and a source of numerous bioactive substances with multiple beneficial health effects. -derived polysaccharides are the most valuable compounds, with anticancer, antioxidant, antimicrobial, and immunomodulatory properties. It has been demonstrated that their biological activity depends on the extraction method, which affects monosaccharide composition, molecular weight, branching degrees, and helical conformation. In this review, we discuss the immunomodulatory properties of various polysaccharides from in animal models and in humans.
（Berk.）Pegler，也被称为香菇，是一种受欢迎的食用大型真菌，也是许多具有多种有益健康作用的生物活性物质的来源。-衍生的多糖是最有价值的化合物，具有抗癌、抗氧化、抗菌和免疫调节特性。已经证明，它们的生物活性取决于提取方法，这会影响单糖组成、分子量、支化度和螺旋构象。在这篇综述中，我们讨论了来自不同来源的各种多糖在动物模型和人类中的免疫调节特性。
