College of Sports and Human Sciences, Harbin Sport University, Harbin, China 150008.
College of Sport Humanistic Sociology, Harbin Sport University, Harbin, China 150008.
Comput Math Methods Med. 2022 Aug 16;2022:6833196. doi: 10.1155/2022/6833196. eCollection 2022.
With the improvement of people's living standards, how to maintain health and delay aging to improve the quality of life and achieve longevity has become a hot topic of concern. . To investigate the effect of acupuncture combined with exercise on the expression of immune factors in aging rats and its significance in antiaging intervention.
Forty-three SD rats included 12 rats in the control group, and the remaining rats were injected intraperitoneally with D-galactose 500 mg/kg to prepare a subacute aging rat model. The 24 rats that were successfully modeled were divided into acupuncture exercise groups and exercise groups according to the random number table method, with 12 rats in each group. After the modeling, the comparison group did not do any intervention, the exercise group was given aerobic exercise intervention, and the acupuncture exercise group was given acupuncture combined with exercise intervention. The effect of immune factor expression in rats was compared.
The levels of IgM, IgA, and IgG in the acupuncture exercise group were significantly higher than those in the exercise group ( < 0.05). The IL-10 content in the acupuncture exercise group was significantly higher than that in the exercise group ( < 0.05) and was significantly reduced in the acupuncture exercise group compared with the comparison group ( < 0.05). The level of IL-6 in the acupuncture exercise group was significantly lower than that in the exercise group, and the level of IL-6 in the acupuncture exercise group was significantly increased compared with the comparison group ( < 0.05). The C3 and C4 levels in the acupuncture exercise group were significantly higher than those in the exercise group ( < 0.05). The levels of IFN- and TNP- were significantly lower in the acupuncture exercise group than in the exercise group and significantly increased in the acupuncture exercise group compared with the comparison group ( < 0.05).
Ling turtle eight method acupuncture combined with exercise promoted the development of immune organ spleen, enhances the body's immune function and complement system, inhibits the immune inflammatory response and regulates immune balance, reduces the inflammatory response caused by the aging of D-type galactose, and achieves the effect of delaying aging.
随着人们生活水平的提高，如何保持健康、延缓衰老，提高生活质量，实现长寿，已成为人们关注的热点问题。探讨了针灸结合运动对衰老大鼠免疫因子表达的影响及其在抗衰老干预中的意义。
43 只 SD 大鼠，其中 12 只大鼠为对照组，其余大鼠采用腹腔注射 D-半乳糖 500mg/kg 制备亚急性衰老大鼠模型。成功造模的 24 只大鼠按随机数字表法分为针刺运动组和运动组，每组 12 只。造模后，对照组不做任何干预，运动组给予有氧运动干预，针刺运动组给予针刺结合运动干预。比较各组大鼠免疫因子表达的效果。
针刺运动组 IgM、IgA、IgG 水平明显高于运动组（ < 0.05）。针刺运动组 IL-10 含量明显高于运动组（ < 0.05），与对照组相比明显降低（ < 0.05）。针刺运动组 IL-6 水平明显低于运动组，与对照组相比，IL-6 水平明显升高（ < 0.05）。针刺运动组 C3、C4 水平明显高于运动组（ < 0.05）。针刺运动组 IFN-和 TNP-水平明显低于运动组，与对照组相比明显升高（ < 0.05）。
灵龟八法针法结合运动促进免疫器官脾脏的发育，增强机体的免疫功能和补体系统，抑制免疫炎症反应，调节免疫平衡，减轻 D-型半乳糖衰老引起的炎症反应，达到延缓衰老的效果。
