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基于文丘里原理的背负式喷雾消毒系统的性能测试

Performance Testing of a Venturi-Based Backpack Spray Decontamination System.

作者信息

Beswick Alan, Bailey Claire, Crook Brian, Crouch David, Farrant Jayne, Frost Gillian, Stagg Stephen

机构信息

Health and Safety Executive, Buxton, Derbyshire, UK.

3M™ United Kingdom PLC, Skelmersdale, Lancashire, UK.

出版信息

Appl Biosaf. 2020 Mar 1;25(1):28-40. doi: 10.1177/1535676019898299.

DOI:10.1177/1535676019898299
PMID:36033381
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9134619/
Abstract

INTRODUCTION

The performance of 2 disinfectant chemicals, peracetic acid (PAA) and hypochlorous acid (HOCl), was evaluated using a Venturi-nozzle-based light decontamination system (LDS) for delivery. The atomization equipment combined low-pressure air and disinfectant via a handheld lance, producing a fine, dense aerosol. A range of microorganisms, including and () spores, were used as test challenges to evaluate chemicals and equipment.

METHODS

The tests undertaken included assessments over fixed and variable exposure times, use of multiple surface materials, and a live agent challenge.

RESULTS

Over a fixed-time exposure of 60 minutes, aerosolized PAA gave 7- to 8-log reductions of all test challenges, but HOCl was less effective. Material tests showed extensive kill on most surfaces using PAA (≥6-log kill), but HOCl showed more variation (4- to 6-log). Testing using showed measurable PAA induced spore kill inside 5 minutes and >6-log kill at 5 minutes or over. HOCl was less effective.

DISCUSSION

The results demonstrate the importance of testing decontamination systems against a range of relevant microbiological challenges. Disinfectant efficacy may vary depending on product choice, types of challenge microorganisms, and their position in a treated area. The most effective disinfectants demonstrate biocidal efficacy despite these factors.

CONCLUSION

The data confirmed PAA as an effective disinfectant capable of rapidly killing a range of microorganisms, including spores. HOCl was less effective. The LDS system successfully delivered PAA and HOCl over a wide area and could be suitable for a range of frontline biosecurity applications.

摘要

引言

使用基于文丘里喷嘴的光消毒系统(LDS)来输送两种消毒化学品——过氧乙酸(PAA)和次氯酸(HOCl),并对其性能进行评估。雾化设备通过手持喷枪将低压空气和消毒剂混合,产生细小而密集的气溶胶。使用一系列微生物,包括[具体微生物名称1]和[具体微生物名称2]([微生物类型])孢子,作为测试挑战来评估化学品和设备。

方法

所进行的测试包括对固定和可变暴露时间的评估、使用多种表面材料以及活菌挑战。

结果

在60分钟的固定时间暴露下,雾化的PAA对所有测试挑战均有7至8个对数级的杀灭效果,但HOCl的效果较差。材料测试表明,使用PAA时,在大多数表面上有广泛的杀灭效果(≥6个对数级的杀灭),但HOCl的变化更大(4至6个对数级)。使用[具体测试方法或条件]进行测试时,PAA在5分钟内可使孢子有可测量的杀灭效果,在5分钟及以上时间可实现>6个对数级的杀灭。HOCl的效果较差。

讨论

结果表明针对一系列相关微生物挑战测试消毒系统的重要性。消毒效果可能因产品选择、挑战微生物的类型及其在处理区域中的位置而有所不同。尽管存在这些因素,最有效的消毒剂仍能显示出杀菌效果。

结论

数据证实PAA是一种能够快速杀灭包括孢子在内的多种微生物的有效消毒剂。HOCl的效果较差。LDS系统成功地在大面积上输送了PAA和HOCl,可能适用于一系列前线生物安全应用。

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J Appl Microbiol. 2014 Sep;117(3):654-62. doi: 10.1111/jam.12560. Epub 2014 Jun 30.
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