Department of Neurosciences, Dentistry Section, University of Padova, Via Giustiniani 2, 35128, Padua, Italy.
Department of Oral Surgery, University Clinic of Düsseldorf, Moorenstrasse 5, 40225, Düsseldorf, Germany.
Int J Implant Dent. 2022 Aug 29;8(1):33. doi: 10.1186/s40729-022-00433-3.
This systematic review aimed at assessing the effect of the repositioned bone lid on bone augmentation in lateral sinus lift in pre-clinical in vivo and clinical studies. Secondary aims were to report on the healing of the bone window and to assess the implant survival rate.
Animal and human studies comparing lateral maxillary sinus floor elevation in combination or not with the repositioned bone lid were retrieved from MEDLINE (PubMed), Web of Science and Cochrane online library. Studies published in English up to April 2022 and reporting on histological and/or radiographic outcomes were considered. Case reports, case series and reviews were excluded. A hand search was also conducted. Risk of bias was assessed and meta-analysis performed to investigate the effect of the bone lid on new bone formation.
After screening, 5 animal studies (4 in rabbits, 1 in sheep) and 2 clinical studies (1 RCT, 1 case-control) were included. Meta-analysis confirmed a higher new bone formation in rabbits at 2 and 8 weeks using the bone lid. The two clinical studies investigated lateral sinus lift with concomitant implant placement and reported similar results and high short-term implant success rate in both test and control groups.
The meta-analysis provided moderate evidence that the repositioned bone lid favored the formation of new bone to a higher extent as compared to resorbable membranes in animal studies. Implant success seems not to be influenced by the technique in the short term.
本系统评价旨在评估在临床前体内和临床研究中重新定位的骨盖在外侧窦提升中对骨增强的效果。次要目的是报告骨窗的愈合情况，并评估种植体存活率。
从 MEDLINE（PubMed）、Web of Science 和 Cochrane 在线图书馆中检索了比较上颌窦外侧底提升并结合或不结合重新定位骨盖的动物和人体研究。纳入了发表于 2022 年 4 月之前的英文研究，并报告了组织学和/或影像学结果。排除了病例报告、病例系列和综述。还进行了手工检索。评估了偏倚风险，并进行了荟萃分析以研究骨盖对新骨形成的影响。
经过筛选，纳入了 5 项动物研究（4 项在兔子中，1 项在绵羊中）和 2 项临床研究（1 项 RCT，1 项病例对照）。荟萃分析证实，在 2 周和 8 周时，使用骨盖的兔子有更高的新骨形成。这两项临床研究都调查了伴有种植体植入的外侧窦提升，并报告了类似的结果和两组测试和对照组的高短期种植体成功率。
荟萃分析提供了中等证据，表明与可吸收膜相比，重新定位的骨盖在动物研究中更有利于形成更多的新骨。在短期内，种植体的成功似乎不受技术的影响。
