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基于三级医院不同临界限值的死产流行病学。

Epidemiology of stillbirths based on different gestational thresholds at a tertiary hospital.

机构信息

Department of Maternal Fetal Medicine, KK Women's and Children's Hospital, Singapore.

Division of Obstetrics and Gynaecology, KK Women's and Children's Hospital, Singapore.

出版信息

Singapore Med J. 2022 Jun;63(6):307-312. doi: 10.11622/smedj.2020173. Epub 2020 Dec 2.

DOI:10.11622/smedj.2020173
PMID:36043307
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9329547/
Abstract

INTRODUCTION

The stillbirth rate (SBR) is an important public health indicator. We studied the distribution of maternal and fetal characteristics and time trends of the SBR at KK Women's and Children's Hospital (KKH), Singapore, from 2004 to 2016 based on various definitions of stillbirth.

METHODS

Data was obtained from the Data Warehouse and Stillbirth Reporting System of KKH from 2004 to 2016. SBRs were calculated based on three definitions (fetal deaths at ≥ 20 weeks, 24 weeks or 28 weeks of gestation per 1,000 total births) and were described with maternal and fetal characteristics, and by year.

RESULTS

From 2004 to 2016, the SBR declined by 44.7%, 25.5% and 18.9% based on Definitions I, II and III, respectively. The SBR at KKH in 2016 was 5.2 (Definition I), 4.1 (Definition II) and 3.0 (Definition III) per 1,000 total births. The SBR was significantly higher in women aged ≥ 35 years, nulliparas and female fetuses. The number of live births at 24-27 weeks of gestation was more than four times higher than that of stillbirths (822 vs. 176). There were 104 (12.7%) neonatal deaths during this gestation period, giving a high survival rate of 87.3%.

CONCLUSION

The SBR in KKH is relatively lower than that in other developed countries. There is a need to consider revising our hospital and national definitions of the stillbirth lower boundary from 28 weeks to 24 weeks of gestation. This would allow us to make better comparisons with other developed countries, in line with improvements in healthcare.

摘要

引言

死胎率(stillbirth rate,SBR)是一个重要的公共卫生指标。我们研究了 2004 年至 2016 年期间新加坡 KK 妇女儿童医院(KK Women's and Children's Hospital,KKH)根据不同的死胎定义,SBR 的分布、母婴特征和时间趋势。

方法

数据来自 KKH 的数据仓库和死胎报告系统,时间跨度为 2004 年至 2016 年。根据三种定义(妊娠 20 周及以上、24 周或 28 周及以上的胎儿死亡每 1000 例总分娩数)计算 SBR,并按母亲和胎儿特征以及年份进行描述。

结果

2004 年至 2016 年,基于定义 I、II 和 III,SBR 分别下降了 44.7%、25.5%和 18.9%。2016 年 KKH 的 SBR 分别为每 1000 例总分娩数 5.2(定义 I)、4.1(定义 II)和 3.0(定义 III)。≥35 岁的女性、初产妇和女性胎儿的 SBR 显著更高。妊娠 24-27 周的活产数是死产数的四倍多(822 比 176)。在此期间有 104 例(12.7%)新生儿死亡,存活率高达 87.3%。

结论

KKH 的 SBR 相对低于其他发达国家。需要考虑将我们医院和国家的死胎下限定义从 28 周修订为 24 周,以与其他发达国家进行更好的比较,并与医疗保健的改善相适应。

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