• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

由DF-2引起的败血症。隐球菌乳胶凝集试验假阳性结果的原因。

Septicemia due to DF-2. Cause of a false-positive cryptococcal latex agglutination result.

作者信息

Westerink M A, Amsterdam D, Petell R J, Stram M N, Apicella M A

出版信息

Am J Med. 1987 Jul;83(1):155-8. doi: 10.1016/0002-9343(87)90512-2.

DOI:10.1016/0002-9343(87)90512-2
PMID:3605167
Abstract

A previously healthy 26-year-old man presented with fever, headache, skin rash, and thrombocytopenia. Cultures of blood and cerebrospinal fluid yielded a fastidious gram-negative bacillus, identified as DF-2. A unique feature of this case was the presence of a false-positive latex agglutination result for cryptococcal antigen in the cerebrospinal fluid in the absence of pleocytosis. Additional laboratory studies, which included indirect immunofluorescence and sodium dodecyl sulfate-polyacrylamide gel electrophoresis, however, failed to reveal common antigenic surface components between these organisms.

摘要

一名既往健康的26岁男性出现发热、头痛、皮疹和血小板减少。血液和脑脊液培养分离出一种苛求革兰阴性杆菌,鉴定为DF-2。该病例的一个独特特征是脑脊液中隐球菌抗原乳胶凝集试验结果呈假阳性,而无细胞增多。然而,包括间接免疫荧光和十二烷基硫酸钠-聚丙烯酰胺凝胶电泳在内的其他实验室研究未能揭示这些微生物之间常见的表面抗原成分。

相似文献

1
Septicemia due to DF-2. Cause of a false-positive cryptococcal latex agglutination result.由DF-2引起的败血症。隐球菌乳胶凝集试验假阳性结果的原因。
Am J Med. 1987 Jul;83(1):155-8. doi: 10.1016/0002-9343(87)90512-2.
2
False positive latex tests for cryptococcal antigen in cerebrospinal fluid.脑脊液中隐球菌抗原乳胶试验的假阳性结果
J Clin Pathol. 1982 Feb;35(2):244-5. doi: 10.1136/jcp.35.2.244.
3
Sensitivity and specificity of a latex agglutination test for detection of cryptococcal antigen in meningitis.用于检测脑膜炎中隐球菌抗原的乳胶凝集试验的敏感性和特异性。
S Afr Med J. 1987 Apr 18;71(8):510-2.
4
False-positive cryptococcal antigen test and cervical prevertebral abscess.隐球菌抗原检测假阳性与颈椎前间隙脓肿
JAMA. 1978 Oct 27;240(18):1982-3.
5
False-negative cerebrospinal fluid cryptococcal latex agglutination tests for patients with culture-positive cryptococcal meningitis.脑脊液隐球菌乳胶凝集试验对培养阳性的隐球菌性脑膜炎患者呈假阴性结果。
J Clin Microbiol. 1993 Sep;31(9):2519-22. doi: 10.1128/jcm.31.9.2519-2522.1993.
6
False-positive reactions in the latex agglutination test for Cryptococcus neoformans antigen.新型隐球菌抗原乳胶凝集试验中的假阳性反应。
J Clin Microbiol. 1991 Jun;29(6):1260-1. doi: 10.1128/jcm.29.6.1260-1261.1991.
7
Case report: false negative serum cryptococcal latex agglutination test in a patient with disseminated cryptococcal disease.病例报告:一名播散性隐球菌病患者血清隐球菌乳胶凝集试验呈假阴性
J Int Assoc Provid AIDS Care. 2015 Mar-Apr;14(2):123-6. doi: 10.1177/2325957414555233. Epub 2014 Oct 20.
8
Detection of cryptococcal antigen. Comparison of two latex agglutination tests.隐球菌抗原的检测。两种乳胶凝集试验的比较。
Am J Clin Pathol. 1981 Jan;75(1):106-9. doi: 10.1093/ajcp/75.1.106.
9
False-negative cryptococcal antigen test.隐球菌抗原检测假阴性
JAMA. 1980 Sep 19;244(12):1359.
10
Comparison of three commercial cryptococcal latex kits for detection of cryptococcal antigen.三种用于检测隐球菌抗原的商用隐球菌乳胶试剂盒的比较。
J Clin Microbiol. 1983 Nov;18(5):1127-30. doi: 10.1128/jcm.18.5.1127-1130.1983.

引用本文的文献

1
Early diagnosis of cryptococcal meningoencephalitis in HIV-negative patients: Integration of brain MRI and clinical findings.HIV阴性患者隐球菌性脑膜脑炎的早期诊断:脑MRI与临床发现的整合
eNeurologicalSci. 2025 Jan 9;38:100552. doi: 10.1016/j.ensci.2025.100552. eCollection 2025 Mar.
2
False positive detection of serum cryptococcal antigens due to insufficient sample dilution: A case series.因样本稀释不足导致血清隐球菌抗原假阳性检测:病例系列
World J Clin Cases. 2023 Mar 16;11(8):1837-1846. doi: 10.12998/wjcc.v11.i8.1837.
3
Capnocytophaga canimorsus Meningitis: Diagnosis Using Polymerase Chain Reaction Testing and Systematic Review of the Literature.
犬咬二氧化碳嗜纤维菌性脑膜炎:应用聚合酶链反应检测进行诊断及文献系统综述
Infect Dis Ther. 2019 Mar;8(1):119-136. doi: 10.1007/s40121-019-0233-6. Epub 2019 Jan 31.
4
Low Cryptococcus Antigen Titers as Determined by Lateral Flow Assay Should Be Interpreted Cautiously in Patients without Prior Diagnosis of Cryptococcal Infection.对于既往未诊断为隐球菌感染的患者,通过侧流分析法测定的低隐球菌抗原滴度结果应谨慎解读。
J Clin Microbiol. 2017 Aug;55(8):2472-2479. doi: 10.1128/JCM.00751-17. Epub 2017 May 31.
5
Integrated therapy for HIV and cryptococcosis.HIV与隐球菌病的综合治疗
AIDS Res Ther. 2016 Nov 29;13(1):42. doi: 10.1186/s12981-016-0126-7.
6
Utility of routine testing of bronchoalveolar lavage fluid for cryptococcal antigen.支气管肺泡灌洗 fluid 进行隐球菌抗原常规检测的效用
J Clin Microbiol. 1998 Oct;36(10):3088-9. doi: 10.1128/JCM.36.10.3088-3089.1998.
7
Guidelines for the investigation of invasive fungal infections in haematological malignancy and solid organ transplantation. British Society for Medical Mycology.血液系统恶性肿瘤和实体器官移植中侵袭性真菌感染的调查指南。英国医学真菌学会。
Eur J Clin Microbiol Infect Dis. 1997 Jun;16(6):424-36. doi: 10.1007/BF02471906.
8
High detection rates of cryptococcal antigen in pulmonary cryptococcosis by Eiken latex agglutination test with pronase pretreatment.经链霉蛋白酶预处理的艾肯乳胶凝集试验对肺隐球菌病中隐球菌抗原的高检出率
Mycopathologia. 1993 Aug;123(2):75-9. doi: 10.1007/BF01365083.
9
Elimination of false-positive serum reactivity in latex agglutination test for cryptococcal antigen in human immunodeficiency virus-infected population.消除人类免疫缺陷病毒感染人群中隐球菌抗原乳胶凝集试验的假阳性血清反应性。
J Clin Microbiol. 1994 Sep;32(9):2158-61. doi: 10.1128/jcm.32.9.2158-2161.1994.
10
Interference by hydroxyethyl starch used for vascular filling in latex agglutination test for cryptococcal antigen.用于血管填充的羟乙基淀粉在隐球菌抗原乳胶凝集试验中的干扰作用。
J Clin Microbiol. 1995 Jul;33(7):1917-9. doi: 10.1128/jcm.33.7.1917-1919.1995.