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嗅觉脑电图与行为的关系:空间分析

Relation of olfactory EEG to behavior: spatial analysis.

作者信息

Freeman W J, Baird B

出版信息

Behav Neurosci. 1987 Jun;101(3):393-408. doi: 10.1037//0735-7044.101.3.393.

DOI:10.1037//0735-7044.101.3.393
PMID:3606812
Abstract

The hypothesis that odor-specific patterns of mitral cell activity during odor discrimination might be found in the corresponding spatial patterns of electroencephalogram (EEG) amplitude over a surgically accessible segment of the bulbar surface was tested in rabbits with chronically implanted electrode arrays. The spatial spectrum of the bulbar EEG was derived and compared with the spectrum predicted for the granule cell generator. Spatial filters were devised to identify, enhance, or remove the granule cell contribution to the EEG. Spatial deconvolution was applied to the filtered granule cell activity patterns to correct for distortion caused by volume conduction. The results indicated that the bulb generated odor-specific spatial patterns in rabbits trained to discriminate between two odors. The odor-specific information was not localizable to subsets of channels. This suggested that the discriminative output of the bulb involved the entire structure, even though the receptor input was delivered to limited subsets of mitral cells.

摘要

在慢性植入电极阵列的兔子身上,对这样一个假设进行了测试:在气味辨别过程中,二尖瓣细胞活动的气味特异性模式可能会在延髓表面手术可及区域的脑电图(EEG)振幅的相应空间模式中被发现。推导了延髓脑电图的空间频谱,并将其与颗粒细胞发生器预测的频谱进行比较。设计了空间滤波器来识别、增强或去除颗粒细胞对脑电图的贡献。对滤波后的颗粒细胞活动模式应用空间反卷积,以校正由体积传导引起的失真。结果表明,在经过训练以区分两种气味的兔子中,延髓产生了气味特异性空间模式。气味特异性信息不能定位到通道子集。这表明,即使受体输入传递到有限的二尖瓣细胞子集,延髓的辨别输出也涉及整个结构。

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