Lee Ting-Wei, Chao Tzu-Yi, Chang Hui-Wen, Cheng Yeong-Hsiang, Wu Ching-Ho, Chang Yen-Chen
Graduate Institute of Molecular and Comparative Pathobiology, School of Veterinary Medicine, National Taiwan University, No. 1, Section 4, Roosevelt Rd., Taipei 106216, Taiwan.
Institute of Veterinary Clinical Science, School of Veterinary Medicine, National Taiwan University, Taipei 10617, Taiwan.
Animals (Basel). 2022 Aug 25;12(17):2187. doi: 10.3390/ani12172187.
-fermented products (BLFP) are probiotics with antibacterial, antiviral, and anti-inflammatory properties that can improve growth performance. This study aimed to compare the fecal microbiota of diarrheal cats with chronic diarrhea ( = 8) with that of healthy cats ( = 4) from the same household using next-generation sequencing, and evaluate the effectiveness of oral administration of BLFP in relieving clinical signs and altering the intestinal microbiota in diarrheal cats. Six out of eight diarrheal cats showed clinical improvement after BLFP administration for 7 days, and the stool condition of the other two was normal. A higher / ratio was noted in the feces of diarrheal cats without clinical improvement as compared with those in the healthy cats and in the diarrheal cats with clinical improvement after receiving BLFP. The phylum and class decreased significantly in diarrheal cats regardless of BLFP administration. spp., , and which belong to the cluster XIVa and have been reported as beneficial to intestinal health, increased significantly in feces after treatment. Furthermore, also significantly decreased in diarrheal cats after BLFP administration. Overall, BLFP could be a potential probiotic to relieve gastrointestinal symptoms and improve fecal microbiota in cats with chronic diarrhea.
发酵产品（BLFP）是具有抗菌、抗病毒和抗炎特性的益生菌，可改善生长性能。本研究旨在使用下一代测序技术比较来自同一家庭的慢性腹泻腹泻猫（n = 8）和健康猫（n = 4）的粪便微生物群，并评估口服BLFP对缓解腹泻猫临床症状和改变肠道微生物群的有效性。8只腹泻猫中有6只在服用BLFP 7天后临床症状改善，另外两只的粪便状况正常。与健康猫和接受BLFP后临床症状改善的腹泻猫相比，未临床改善的腹泻猫粪便中的/比值更高。无论是否给予BLFP，腹泻猫的门和纲均显著减少。属于聚类XIVa且已报道对肠道健康有益的 spp.、 和 在治疗后粪便中显著增加。此外，给予BLFP后腹泻猫的 也显著减少。总体而言，BLFP可能是缓解慢性腹泻猫胃肠道症状和改善粪便微生物群的潜在益生菌。
