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眼表疾病成像方式的最新进展。

Update on imaging modalities for ocular surface pathologies.

作者信息

Alvarez Osmel P, Galor Anat, AlBayyat Ghada, Karp Carol L

机构信息

Bascom Palmer Eye Institute, Department of Ophthalmology, University of Miami, Miami, FL, USA.

Bascom Palmer Eye Institute, Department of Ophthalmology, University of Miami, Miami, FL, USA; Department of Ophthalmology, Miami Veterans Administration Medical Center, Miami, Florida, USA.

出版信息

Curr Ophthalmol Rep. 2021 Jun;9(2):39-47. doi: 10.1007/s40135-021-00265-1. Epub 2021 May 18.

DOI:10.1007/s40135-021-00265-1
PMID:36093383
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9455836/
Abstract

PURPOSE OF REVIEW

To discuss recent studies of imaging modalities for ocular surface pathologies.

RECENT FINDINGS

Novel micro-ocular coherence tomography technology can produce high-resolution images of corneal cellular and nervous structures. Ocular coherence tomography angiography can aid in detecting early stage limbal stem cell deficiency. Several studies used confocal microscopy to evaluate corneal nerve metrics and morphology.

SUMMARY

The applications of anterior segment optical coherence tomography, anterior segment optical coherence tomography angiography, ultrasound biomicroscopy, and confocal microscopy are useful technologies for imaging the ocular surface. Several studies have used artificial intelligence in combination with imaging technologies to create reliable and effective systems to detect and visualize ocular surface pathologies. AS OCT continues to be a key imaging tool and future development of μOCT technology may further enhance its utility.

摘要

综述目的

讨论近期眼表疾病成像方式的研究。

最新发现

新型微光学相干断层扫描技术可生成角膜细胞和神经结构的高分辨率图像。光学相干断层扫描血管造影有助于检测早期角膜缘干细胞缺乏。多项研究使用共聚焦显微镜评估角膜神经指标和形态。

总结

眼前段光学相干断层扫描、眼前段光学相干断层扫描血管造影、超声生物显微镜和共聚焦显微镜的应用是眼表成像的有用技术。多项研究已将人工智能与成像技术相结合,以创建可靠且有效的系统来检测和可视化眼表疾病。眼前段光学相干断层扫描仍然是关键的成像工具,微光学相干断层扫描技术的未来发展可能会进一步提高其效用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/12cb/9455836/84e73393fff3/nihms-1787847-f0005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/12cb/9455836/ac9688c62bf7/nihms-1787847-f0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/12cb/9455836/c01479bc08ac/nihms-1787847-f0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/12cb/9455836/d7c2da2cd4d7/nihms-1787847-f0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/12cb/9455836/3227d17474c9/nihms-1787847-f0004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/12cb/9455836/84e73393fff3/nihms-1787847-f0005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/12cb/9455836/ac9688c62bf7/nihms-1787847-f0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/12cb/9455836/c01479bc08ac/nihms-1787847-f0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/12cb/9455836/d7c2da2cd4d7/nihms-1787847-f0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/12cb/9455836/3227d17474c9/nihms-1787847-f0004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/12cb/9455836/84e73393fff3/nihms-1787847-f0005.jpg

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Corneal Edema Visualization With Optical Coherence Tomography Using Deep Learning: Proof of Concept.基于深度学习的光学相干断层扫描术对角膜水肿的可视化:概念验证。
Cornea. 2021 Oct 1;40(10):1267-1275. doi: 10.1097/ICO.0000000000002640.
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Corneal sub-basal nerve plexus microneuromas in individuals with and without dry eye.
角膜基底下神经丛微神经瘤在干眼和非干眼个体中的研究。
Br J Ophthalmol. 2022 May;106(5):616-622. doi: 10.1136/bjophthalmol-2020-317891. Epub 2021 Jan 4.
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Micro-optical coherence tomography for high-resolution morphologic imaging of cellular and nerval corneal micro-structures.用于细胞和神经角膜微结构高分辨率形态学成像的显微光学相干断层扫描技术
Biomed Opt Express. 2020 Sep 28;11(10):5920-5933. doi: 10.1364/BOE.402971. eCollection 2020 Oct 1.
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