Alshamsan Bader
Department of Medicine, Qassim Medical College, Qassim University, Qassim, Saudi Arabia.
Int J Health Sci (Qassim). 2022 Sep-Oct;16(5):21-31.
The objectives of the study was to describe cancer incidence in the Qassim region and compare it with the national incidence rate for all reported cancer sites over 15-years (2002-2016).
A descriptive analysis was conducted using the Saudi Cancer Registry (SCR) data. The annual percentage change (APC) was computed using Joinpoint regression software.
The Qassim region contributed to 4.3% ( = 6118) of the total cancer burden in Saudi Arabia (SA). Cancer incidence increased throughout the study period; however, it did not reach statistical significance. The age-standardized rate (ASR) per 100,000 persons was higher in females 68.8 (95% CI: 60.2-77.3) than in males 57.0 (95% CI: 51.9-62.12), < 0.001. Since 2011, colon and rectal cancers have replaced non-Hodgkin lymphoma (NHL) and liver cancer as the leading cancer types among men. In women, the breast is the leading cancer type, and since 2014, the colon and uterus replaced the thyroid and NHL as the second and fourth-most common cancers. ASR of nasopharyngeal, esophageal, and Hodgkin's lymphoma were significantly higher in Qassim as compared to SA. The following cancer types showed significant APC (2002-2016): in males; colon: APC = 7.3%, rectum: APC = 6.1%, bone: APC = 8.3%, and esophageal: APC -5.1%. In females; breast: APC = 6%, colon: APC = 7.2%, uterus: APC = 10.1%, kidney: APC = 15.3%, bone: APC = 8.1%, skin non-melanoma: APC = -8.1%, and myeloid leukemia: APC -14.2%.
The significant changes in cancer incidence in Qassim warrant further studies on the risk factors and preventive measures.
本研究的目的是描述卡西姆地区的癌症发病率，并将其与15年（2002 - 2016年）期间所有报告癌症部位的全国发病率进行比较。
使用沙特癌症登记处（SCR）的数据进行描述性分析。使用Joinpoint回归软件计算年度百分比变化（APC）。
卡西姆地区占沙特阿拉伯（SA）总癌症负担的4.3%（n = 6118）。在整个研究期间癌症发病率有所上升，但未达到统计学显著性。每10万人的年龄标准化率（ASR）女性为68.8（95%CI：60.2 - 77.3）高于男性57.0（95%CI：51.9 - 62.12），P < 0.001。自2011年以来，结肠癌和直肠癌已取代非霍奇金淋巴瘤（NHL）和肝癌成为男性中主要的癌症类型。在女性中，乳腺癌是主要的癌症类型，自2014年以来，结肠癌和子宫癌取代甲状腺癌和NHL成为第二和第四常见的癌症。与沙特阿拉伯相比，卡西姆地区鼻咽癌、食管癌和霍奇金淋巴瘤的ASR显著更高。以下癌症类型在2002 - 2016年期间显示出显著的APC：男性中，结肠癌：APC = 7.3%，直肠癌：APC = 6.1%，骨癌：APC = 8.3%，食管癌：APC = -5.1%。女性中，乳腺癌：APC = 6%，结肠癌：APC = 7.2%，子宫癌：APC = 10.1%，肾癌：APC = 15.3%，骨癌：APC = 8.1%，皮肤非黑色素瘤：APC = -8.1%，髓系白血病：APC = -14.2%。
卡西姆地区癌症发病率的显著变化值得对危险因素和预防措施进行进一步研究。
