Department of Medicine, Jinnah Sindh Medical University, Karachi, Pakistan.
Department of Medicine, Lahore Medical and Dental College, Lahore, Pakistan.
Medicine (Baltimore). 2022 Sep 2;101(35):e30406. doi: 10.1097/MD.0000000000030406.
The human monkeypox is an emerging zoonotic orthopoxvirus with a clinical presentation similar to that of smallpox. It is difficult to differentiate monkeypox from other orthopedic infections, and laboratory diagnosis is the primary component of disease identification and monitoring. However, current diagnostics are time-consuming, and new tests are needed for rapid and precise diagnosis. Most cases have been reported in Central Africa; however, an increasing number of cases have been reported in Europe, the United States of America (USA), Australia, and the United Arab Emirates. Although investigation of the current global outbreak is still ongoing, viral transmission seems to have occurred during crowded events in Spain and Belgium. New therapeutics and vaccines are being deployed for the treatment and prevention of monkeypox, and more research on the epidemiology, biology, and ecology of the virus in endemic areas is required to understand and prevent further global outbreaks.
人类猴痘是一种新兴的正痘病毒，其临床表现与天花相似。猴痘很难与其他骨科感染区分开来，实验室诊断是疾病识别和监测的主要组成部分。然而，目前的诊断方法耗时较长，需要新的检测方法来快速准确地诊断。大多数病例报告发生在中非；然而，欧洲、美利坚合众国（美国）、澳大利亚和阿拉伯联合酋长国报告的病例数量正在逐渐增加。尽管目前仍在对全球疫情进行调查，但病毒似乎是在西班牙和比利时的拥挤活动中传播的。正在为猴痘的治疗和预防部署新的疗法和疫苗，需要对流行地区的病毒流行病学、生物学和生态学进行更多研究，以了解和预防进一步的全球疫情爆发。
