Zhang Xin, Bai Rushui, Sun Qiannan, Zhuang Zimeng, Zhang Yunfan, Chen Si, Han Bing
Department of Orthodontics, School and Hospital of Stomatology, Peking University, Beijing, China.
National Engineering Laboratory for Digital and Material Technology of Stomatology & Beijing Key Laboratory of Digital Stomatology, Beijing, China.
Front Bioeng Biotechnol. 2022 Aug 30;10:1001616. doi: 10.3389/fbioe.2022.1001616. eCollection 2022.
Most oral diseases originate from biofilms whose formation is originated from the adhesion of salivary proteins and pioneer bacteria. Therefore, antimicrobial materials are mainly based on bactericidal methods, most of which have drug resistance and toxicity. Natural antifouling surfaces inspire new antibacterial strategies. The super wettable surfaces of lotus leaves and fish scales prompt design of biomimetic oral materials covered or mixed with super wettable materials to prevent adhesion. Bioinspired slippery surfaces come from pitcher plants, whose porous surfaces are infiltrated with lubricating liquid to form superhydrophobic surfaces to reduce the contact with liquids. It is believed that these new methods could provide promising directions for oral antimicrobial practice, improving antimicrobial efficacy.
大多数口腔疾病起源于生物膜，其形成源于唾液蛋白和先锋细菌的黏附。因此，抗菌材料主要基于杀菌方法，其中大多数具有耐药性和毒性。天然防污表面启发了新的抗菌策略。荷叶和鱼鳞的超润湿性表面促使人们设计覆盖或混合超润湿性材料的仿生口腔材料以防止黏附。受生物启发的光滑表面来自猪笼草，其多孔表面被润滑液浸润形成超疏水表面以减少与液体的接触。据信，这些新方法可为口腔抗菌实践提供有前景的方向，提高抗菌效果。
