Department of Biomedical Sciences, College of Medicine, Debre Berhan University, Debre Berhan, Ethiopia.
Department of Internal Medicine, College of Medicine, Debre Berhan University, Debre Berhan, Ethiopia.
Behav Neurol. 2022 Sep 12;2022:1142215. doi: 10.1155/2022/1142215. eCollection 2022.
Acceptance of illness is regarded as an indicator of functioning and predictor of quality of life. However, quality of life of patients with epilepsy in sub-Saharan countries worsen because of low medication adherence, increased morbidity and mortality, and the stigmatization associated with the disease. This research is aimed at assessing the level of acceptance of illness of patients with epilepsy and associated quality of life in North-East Ethiopia. . A cross-sectional study was conducted from January to June 2021 at the Debre Berhan Referral Hospital, North-East Ethiopia. A total of 78 patients with epilepsy aged more than 18 years were randomly selected and assessed using Quality of Life in Epilepsy Inventory 31 and acceptance of illness scale. In addition, authors owned questionnaire were used to evaluate the sociodemographic and clinical characteristics of the patients. value < 0.05 at 95% confidence level was considered to be statistically significant in all the analysis. . The study participants' age varied between 18 and 67 years with the mean age of 28.9 years. Phenobarbital was the most used (73.9%) antiepileptic drug, and 68.7% ( = 66) of the patients seizure was controlled. 72.9% ( = 70) of the patients had medium acceptance of illness (scored 20-30), while 17.7% ( = 17) had low illness acceptance level (scored 8-19), and 9.4% ( = 9) had high acceptance of illness (scored 31-40). The mean of overall acceptance of illness among epileptic patients was 21.04 ± 7.21. The overall score of QOLIE-31 was 79.14 ± 25.46, and the highest mean score was for cognitive (83.5 ± 27.1), while the lowest mean score was that of medication effect (72.7 ± 28.7). Five of the seven QOLIE-31 components correlated significantly with level of acceptance of illness. Cognitive domain ( = 0.498, < 0.001) demonstrated the highest correlation followed by overall quality of life ( = 0.489, < 0.001), seizure worry ( = 0.433, < 0.001), energy/fatigue ( = 0.342, < 0.001), and emotional well-being ( = 0.278, < 0.001). . Patients with epilepsy in the study area had medium acceptance of illness, and nearly half of them had mean and more than the mean quality of life. The patients' acceptance of illness was significantly associated with overall quality of life, seizure worry, emotional well-being, and cognitive domain of the patients.
接受疾病被认为是功能的指标和生活质量的预测因素。然而，撒哈拉以南非洲国家的癫痫患者的生活质量恶化，因为药物依从性低、发病率和死亡率增加，以及与疾病相关的污名化。这项研究旨在评估东北埃塞俄比亚癫痫患者的疾病接受程度和相关生活质量。 . 这是一项横断面研究，于 2021 年 1 月至 6 月在东北埃塞俄比亚的德布雷贝汉转诊医院进行。共随机选择了 78 名年龄在 18 岁以上的癫痫患者，并使用癫痫生活质量量表 31 版和疾病接受量表进行评估。此外，作者还使用问卷评估了患者的社会人口学和临床特征。 值 < 0.05，置信水平为 95%，在所有分析中均具有统计学意义。. 研究参与者的年龄在 18 岁至 67 岁之间，平均年龄为 28.9 岁。苯巴比妥是最常用的（73.9%）抗癫痫药物，68.7%（=66）的患者癫痫发作得到控制。72.9%（=70）的患者对疾病有中等程度的接受度（得分 20-30），17.7%（=17）的患者对疾病的接受度较低（得分 8-19），9.4%（=9）的患者对疾病的接受度较高（得分 31-40）。癫痫患者整体疾病接受程度的平均值为 21.04±7.21。癫痫患者生活质量量表 31 版的总分为 79.14±25.46，认知方面的平均得分最高（83.5±27.1），而药物效果方面的平均得分最低（72.7±28.7）。七个癫痫生活质量量表 31 版的组成部分中有五个与疾病接受程度显著相关。认知领域（=0.498，<0.001）的相关性最高，其次是整体生活质量（=0.489，<0.001）、癫痫发作担忧（=0.433，<0.001）、能量/疲劳（=0.342，<0.001）和情绪健康（=0.278，<0.001）。. 研究地区的癫痫患者对疾病的接受程度处于中等水平，近一半的患者的生活质量处于平均水平或高于平均水平。患者对疾病的接受程度与整体生活质量、癫痫发作担忧、情绪健康和认知领域显著相关。
