Anisha Grace Sathyanesan, Padmakumari Savitha, Patel Anil Kumar, Pandey Ashok, Singhania Reeta Rani
Post-Graduate and Research Department of Zoology, Government College for Women, Thiruvananthapuram 695014, India.
Department of Marine Environmental Engineering, National Kaohsiung University of Science and Technology, Kaohsiung City 81157, Taiwan.
Bioengineering (Basel). 2022 Sep 14;9(9):472. doi: 10.3390/bioengineering9090472.
The marine macroalgae produce a collection of bioactive polysaccharides, of which the sulfated heteropolysaccharide fucoidan produced by brown algae of the class Phaeophyceae has received worldwide attention because of its particular biological actions that confer nutritional and health benefits to humans and animals. The biological actions of fucoidan are determined by their structure and chemical composition, which are largely influenced by the geographical location, harvest season, extraction process, etc. This review discusses the structure, chemical composition and physicochemical properties of fucoidan. The biological action of fucoidan and its applications for human health, tissue engineering, regenerative medicine and drug delivery are also addressed. The industrial scenario and prospects of research depicted would give an insight into developing fucoidan as a commercially viable and sustainable bioactive material in the nutritional and pharmacological sectors.
海洋大型藻类产生一系列生物活性多糖，其中褐藻门褐藻产生的硫酸化杂多糖岩藻聚糖因其赋予人类和动物营养与健康益处的特殊生物学作用而受到全球关注。岩藻聚糖的生物学作用取决于其结构和化学组成，而结构和化学组成在很大程度上受地理位置、收获季节、提取工艺等因素影响。本综述讨论了岩藻聚糖的结构、化学组成和物理化学性质。还阐述了岩藻聚糖的生物学作用及其在人类健康、组织工程、再生医学和药物递送方面的应用。所描述的研究的产业情况和前景将有助于深入了解将岩藻聚糖开发成为营养和药理学领域具有商业可行性和可持续性的生物活性材料。
