Department of Literature and Information of Library, Shenyang Pharmaceutical University, Shenyang 110016, China.
School of Life Science and Biopharmaceutics, Shenyang Pharmaceutical University, Shenyang 110016, China.
Int J Environ Res Public Health. 2022 Sep 17;19(18):11728. doi: 10.3390/ijerph191811728.
This study aims to map the knowledge structure and themes trends of primary ovarian insufficiency (POI) therapy to help researchers rapidly master the hotspots and prospects of POI therapy from the increasing number of publications. The literature search and bibliometric analyses were performed by using Web of Science Core Collection and VOSviewer. Annual publications from 2000 to 2022 continued to increase with some fluctuations. The most productive country, organization, and journal were the USA, Shanghai Jiao Tong University, and , respectively. Harvard University was the organization with the highest citation. and Nelson, L.M. were the most influential journal and author, respectively. Seven clusters separated by keywords association showed the extensive scope of POI therapy. The hotspots of POI therapy were hormone replacement therapy and fertility preservation, and the innovative treatment strategies including in vitro activation and mesenchymal stem cells had development potential. In addition, our result showed that the high-cited articles were published in journals with high impact factors. The paper provides a comprehensive overview of the development and hotspots of POI therapy, allowing researchers to recognize the current status and future directions of POI therapy.
本研究旨在绘制原发性卵巢功能不全（POI）治疗的知识结构和主题趋势图，以帮助研究人员从不断增加的出版物中快速掌握 POI 治疗的热点和前景。文献检索和计量学分析使用了 Web of Science 核心合集和 VOSviewer。2000 年至 2022 年的年度出版物持续增加，略有波动。最具生产力的国家、组织和期刊分别是美国、上海交通大学和 。哈佛大学是被引频次最高的机构。 和 Nelson, L.M. 分别是最有影响力的期刊和作者。通过关键词关联分离的七个聚类显示了 POI 治疗的广泛范围。POI 治疗的热点是激素替代治疗和生育力保存，而体外激活和间充质干细胞等创新治疗策略具有发展潜力。此外，我们的结果表明，高被引文章发表在高影响因子期刊上。本文全面概述了 POI 治疗的发展和热点，使研究人员能够认识到 POI 治疗的现状和未来方向。
