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用于牙科学应用的基于聚甲基丙烯酸甲酯的纳米复合材料:最新进展。

PMMA-Based Nanocomposites for Odontology Applications: A State-of-the-Art.

机构信息

Universidad de Alcalá, Facultad de Ciencias, Departamento de Química Analítica, Química Física e Ingeniería Química, Ctra. Madrid-Barcelona Km. 33.6, 28805 Alcalá de Henares, Madrid, Spain.

出版信息

Int J Mol Sci. 2022 Sep 7;23(18):10288. doi: 10.3390/ijms231810288.

Abstract

Polymethyl methacrylate (PMMA), a well-known polymer of the methacrylate family, is extensively used in biomedicine, particularly in odontological applications including artificial teeth, dentures and denture bases, obturators, provisional or permanent crowns, and so forth. The exceptional PMMA properties, including aesthetics, inexpensiveness, simple manipulation, low density, and adjustable mechanical properties, make it a perfect candidate in the field of dentistry. However, it presents some deficiencies, including weakness regarding hydrolytic degradation, poor fracture toughness, and a lack of antibacterial activity. To further enhance its properties and solve these drawbacks, different approaches can be performed, including the incorporation of nanofillers. In this regard, different types of metallic nanoparticles, metal oxide nanofillers, and carbon-based nanomaterials have been recently integrated into PMMA matrices with the aim to reduce water absorption and improve their performance, namely their thermal and flexural properties. In this review, recent studies regarding the development of PMMA-based nanocomposites for odontology applications are summarized and future perspectives are highlighted.

摘要

聚甲基丙烯酸甲酯(PMMA)是甲基丙烯酸酯家族中一种众所周知的聚合物,广泛应用于生物医学领域,特别是在牙科应用中,包括假牙、义齿和义齿基托、堵塞物、临时或永久牙冠等。PMMA 的特殊性能,包括美观、经济实惠、操作简单、密度低和可调节的机械性能,使其成为牙科领域的理想选择。然而,它也存在一些缺点,包括水解降解方面的弱点、较差的断裂韧性和缺乏抗菌活性。为了进一步提高其性能并解决这些缺点,可以采用不同的方法,包括加入纳米填料。在这方面,最近已经将不同类型的金属纳米粒子、金属氧化物纳米填料和碳基纳米材料整合到 PMMA 基质中,以减少吸水率并改善其性能,即热性能和弯曲性能。在这篇综述中,总结了最近关于用于牙科应用的 PMMA 基纳米复合材料的研究,并强调了未来的展望。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2220/9499310/f6c00737961b/ijms-23-10288-g001.jpg

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