Faculty of Health Sciences, ATH University of Bielsko-Biala, 43-309 Bielsko-Biała, Poland.
Faculty of Mechanical Engineering and Computer Science, ATH University of Bielsko-Biala, 43-309 Bielsko-Biała, Poland.
Int J Mol Sci. 2022 Sep 17;23(18):10899. doi: 10.3390/ijms231810899.
This work contains an analysis of the impact of modifying a bioresorbable polymer-polycaprolactone (PCL)-with various additives on its antibacterial properties. To this end, samples of PCL filament containing various content levels of graphene (GNP), 0.5%, 5%, 10%, were obtained using injection molding. Polymer samples without additives were used for comparison. The next step was to assess the antimicrobial impact of the preparations under study against the following microorganisms: ATCC 25293, ATCC 25922, ATCC 10231. Effective bactericidal activity of PCL with small amount of GNP, especially against and was confirmed. A decrease in this property or even multiplication of microorganisms was observed in direct proportion to the graphene content in the samples.
这项工作分析了用各种添加剂改性可生物吸收聚合物聚己内酯（PCL）对其抗菌性能的影响。为此，通过注塑成型获得了含有不同含量石墨烯（GNP）的 PCL 长丝样品，含量分别为 0.5%、5%和 10%。使用不含添加剂的聚合物样品进行比较。下一步是评估研究中的制剂对以下微生物的抗菌作用：ATCC 25293、ATCC 25922、ATCC 10231。证实了少量 GNP 的 PCL 具有有效的杀菌活性，特别是对 和 。在样品中石墨烯含量成比例地观察到这种性质的降低甚至微生物的繁殖。
