超临界二氧化碳（SC-CO）萃取法提取广藿香中生物活性化合物的特性研究。

Characterization of Bioactive Compounds from Patchouli Extracted via Supercritical Carbon Dioxide (SC-CO) Extraction.

机构信息

Chemical Engineering Department, Universitas Syiah Kuala, Banda Aceh 23111, Indonesia.

ARC-PUIPT Nilam Aceh, Universitas Syiah Kuala, Banda Aceh 23111, Indonesia.

出版信息

Molecules. 2022 Sep 15;27(18):6025. doi: 10.3390/molecules27186025.

DOI:10.3390/molecules27186025

PMID:36144760

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9503852/

Abstract

Patchouli extracts and oils extracted from are essential raw material for the perfume and cosmetics industries, in addition to being used as a natural additive for food flavoring. Steam distillation is a standard method used for plant extraction. However, this method causes thermal degradation of some essential components of the oil. In this study, patchouli was extracted with supercritical carbon dioxide (SC-CO) under different conditions of pressure (10-30 MPa) and temperature (40-80 °C). The chemical components of the crude extracted oil and the functional group were characterized using gas chromatography-mass spectrometry (GC-MS) and Fourier Transform Infrared Spectroscopy (FT-IR). The extraction with supercritical carbon dioxide was shown to provide a higher yield (12.41%) at a pressure of 20 MPa and a temperature of 80 °C. Patchouli alcohol, Azulene, δ-Guaiene, and Seychellene are the main bioactive compounds that GC-MS results have identified. FTIR spectra showed alcohol, aldehyde, and aromatic ring bond stretching peaks. Extraction of patchouli with supercritical carbon dioxide provided a higher yield and a better quality of the crude patchouli oil.

摘要

广藿香提取物和精油是香水和化妆品行业的重要原料，此外还可用作天然食品香料添加剂。水蒸气蒸馏是植物提取的标准方法。然而，这种方法会导致油中某些重要成分的热降解。在这项研究中，使用超临界二氧化碳（SC-CO2）在不同的压力（10-30 MPa）和温度（40-80°C）条件下对广藿香进行了提取。使用气相色谱-质谱联用仪（GC-MS）和傅里叶变换红外光谱仪（FT-IR）对粗提油的化学成分和官能团进行了表征。超临界二氧化碳萃取在压力为 20 MPa、温度为 80°C 时，产率（12.41%）最高。GC-MS 结果表明，广藿香醇、薁、δ-愈创烯和西松烯是主要的生物活性化合物。FTIR 图谱显示了醇、醛和芳环键的伸缩峰。超临界二氧化碳萃取广藿香可获得更高的产率和更优质的粗广藿香油。