Department of Neurosurgery, Helsinki University Hospital, Helsinki, Finland.
Faculty of Medicine, University of Helsinki, Helsinki, Finland.
Acta Neurochir (Wien). 2022 Dec;164(12):3155-3164. doi: 10.1007/s00701-022-05375-8. Epub 2022 Oct 7.
The purpose of the study was to evaluate the long-term outcome after surgery for lumbar disc herniation in a young adult population.
A total of 526 consecutive patients between 18 and 40 years of age who underwent surgery for lumbar disc between 1990 and 2005 were included in the study. The primary outcomes were the need for new lumbar spine surgery during the follow-up and secondary outcomes were short-term subjective outcome, the Oswestry Disability Index (ODI) score, and the ability to carry out employment at the end of the long-term follow-up.
A total of 96% of the patients had a reduction in their symptoms at the clinical follow-up (median of 50 days post-surgery). Twenty-one patients (4.0%) had a reoperation within 28 days. Excluding these early reoperations, 136 patients (26%) had additional lumbar spine surgery and 18 patients (3.4%) underwent lumbar fusion during the follow-up of median 18 years. The annual risk for new surgery was 1.4%. In total, 316 patients (60%) returned the ODI questionnaire, and their mean score was 8.1. Patients with a higher number of additional lumbar spine surgeries (p < 0.001) reported deteriorating ODI scores.
Patients showed excellent short-term recovery from their symptoms. In the long term, the mean ODI score for the patients was comparable to the normative population. However, a notable proportion of the patients required additional lumbar surgery during the follow-up period, and a higher number of lumbar surgeries was associated with poor ODI scores.
本研究旨在评估青年人群腰椎间盘突出症手术后的长期疗效。
本研究共纳入 1990 年至 2005 年间接受手术治疗的 18-40 岁连续 526 例腰椎间盘突出症患者。主要结局为随访期间是否需要再次行腰椎手术,次要结局为短期主观结局、Oswestry 功能障碍指数(ODI)评分以及长期随访结束时的就业能力。
96%的患者在临床随访时症状得到缓解(术后中位数为 50 天)。21 例(4.0%)在 28 天内行再次手术。排除这些早期再手术,136 例(26%)在随访中位数 18 年内接受了额外的腰椎手术,18 例(3.4%)接受了腰椎融合术。每年新手术的风险为 1.4%。共有 316 例患者(60%)返回了 ODI 问卷,其平均评分为 8.1。行更多次额外腰椎手术的患者(p<0.001)报告 ODI 评分恶化。
患者的症状在短期内有明显缓解。长期来看,患者的平均 ODI 评分与常模人群相当。然而,在随访期间,相当一部分患者需要再次行腰椎手术,且手术次数越多,ODI 评分越差。