Muscogiuri Giuseppe, Guaricci Andrea Igoren, Soldato Nicola, Cau Riccardo, Saba Luca, Siena Paola, Tarsitano Maria Grazia, Giannetta Elisa, Sala Davide, Sganzerla Paolo, Gatti Marco, Faletti Riccardo, Senatieri Alberto, Chierchia Gregorio, Pontone Gianluca, Marra Paolo, Rabbat Mark G, Sironi Sandro
Department of Radiology, Istituto Auxologico Italiano IRCCS, San Luca Hospital, Piazzale Brescia 20, 20149 Milan, Italy.
School of Medicine, University of Milano-Bicocca, 20126 Milan, Italy.
J Clin Med. 2022 Sep 26;11(19):5663. doi: 10.3390/jcm11195663.
Sudden cardiac death (SCD) is a potentially fatal event usually caused by a cardiac arrhythmia, which is often the result of coronary artery disease (CAD). Up to 80% of patients suffering from SCD have concomitant CAD. Arrhythmic complications may occur in patients with acute coronary syndrome (ACS) before admission, during revascularization procedures, and in hospital intensive care monitoring. In addition, about 20% of patients who survive cardiac arrest develop a transmural myocardial infarction (MI). Prevention of ACS can be evaluated in selected patients using cardiac computed tomography angiography (CCTA), while diagnosis can be depicted using electrocardiography (ECG), and complications can be evaluated with cardiac magnetic resonance (CMR) and echocardiography. CCTA can evaluate plaque, burden of disease, stenosis, and adverse plaque characteristics, in patients with chest pain. ECG and echocardiography are the first-line tests for ACS and are affordable and useful for diagnosis. CMR can evaluate function and the presence of complications after ACS, such as development of ventricular thrombus and presence of myocardial tissue characterization abnormalities that can be the substrate of ventricular arrhythmias.
心源性猝死(SCD)是一种潜在的致命事件,通常由心律失常引起,而心律失常往往是冠状动脉疾病(CAD)的结果。高达80%的SCD患者伴有CAD。心律失常并发症可能发生在急性冠状动脉综合征(ACS)患者入院前、血运重建过程中以及医院重症监护监测期间。此外,约20%心脏骤停存活的患者会发生透壁性心肌梗死(MI)。对于部分患者,可使用心脏计算机断层血管造影(CCTA)评估ACS的预防情况,通过心电图(ECG)进行诊断,利用心脏磁共振成像(CMR)和超声心动图评估并发症。CCTA可评估胸痛患者的斑块、疾病负担、狭窄情况以及不良斑块特征。ECG和超声心动图是ACS的一线检查方法,价格实惠且对诊断有用。CMR可评估ACS后的心脏功能及并发症情况,如心室血栓的形成以及心肌组织特征异常的存在,这些异常可能是室性心律失常的基础。