• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

一项关于砷的十进制和百分制稀释对大鼠体内砷的潴留和迁移影响的研究。

A study of the effect of decimal and centesimal dilutions of arsenic on the retention and mobilization of arsenic in the rat.

作者信息

Cazin J C, Cazin M, Gaborit J L, Chaoui A, Boiron J, Belon P, Cherruault Y, Papapanayotou C

出版信息

Hum Toxicol. 1987 Jul;6(4):315-20. doi: 10.1177/096032718700600408.

DOI:10.1177/096032718700600408
PMID:3623577
Abstract

Having developed a pharmacokinetic method for studying the fate of orally administered arsenious anhydride by a radioactive tracer method, the influence of Hahnemannian dilutions of arsenicum album on the elimination and retention of this toxin in the rat was then investigated. The effects of centesimal (cH) and decimal (dH) dilutions were studied. All the dilutions studied were found to be active. The strongest effects were observed after the administration of dilutions corresponding to a concentration of 10(-14) (14dH and 7cH). Overall, the decimal dilutions augmented the elimination of arsenic more than the centesimals. The observed results were submitted to mathematical analysis. A mathematical model, which confirms that Hahnemannian dilutions have biological effects which are a direct function of the degree of dilution, was developed.

摘要

通过放射性示踪法建立了一种研究口服亚砷酸酐命运的药代动力学方法后,随后研究了顺势疗法稀释的白砷对大鼠体内这种毒素消除和保留的影响。研究了百分之一(cH)和十分之一(dH)稀释液的效果。所有研究的稀释液都被发现具有活性。在给予相当于10(-14)浓度的稀释液(14dH和7cH)后观察到最强的效果。总体而言,十分之一稀释液比百分之一稀释液更能促进砷的消除。将观察结果进行数学分析。建立了一个数学模型,该模型证实顺势疗法稀释液具有生物学效应,且这种效应是稀释程度的直接函数。

相似文献

1
A study of the effect of decimal and centesimal dilutions of arsenic on the retention and mobilization of arsenic in the rat.一项关于砷的十进制和百分制稀释对大鼠体内砷的潴留和迁移影响的研究。
Hum Toxicol. 1987 Jul;6(4):315-20. doi: 10.1177/096032718700600408.
2
Ameliorating effect of microdoses of a potentized homeopathic drug, Arsenicum Album, on arsenic-induced toxicity in mice.微量增效顺势疗法药物白砷对小鼠砷中毒的改善作用。
BMC Complement Altern Med. 2003 Oct 22;3:7. doi: 10.1186/1472-6882-3-7.
3
Arsenic Trioxide三氧化二砷
4
The effect of infinitesimal drug dilutions on the pharmacokinetics of nalidixic acid and atenolol.微量药物稀释对萘啶酸和阿替洛尔药代动力学的影响。
Br J Clin Pharmacol. 1991 Jul;32(1):39-44. doi: 10.1111/j.1365-2125.1991.tb05610.x.
5
Biological Actions, Electrical Conductance and Silicon-Containing Microparticles of Arsenicum Album Prepared in Plastic and Glass Vials.在塑料瓶和玻璃瓶中制备的白砷的生物活性、电导率及含硅微粒
Homeopathy. 2019 Feb;108(1):12-23. doi: 10.1055/s-0038-1670675. Epub 2018 Oct 5.
6
[Metabolism of arsenic. Uptake of radioactive isotope 74As in rats fed on As203-added feed].[砷的代谢。喂食添加了As2O3饲料的大鼠对放射性同位素74As的摄取]
Nihon Shonika Gakkai Zasshi. 1971 Oct;75(10):973-80.
7
Experimental studies on arsenic absorption routes in rats.大鼠砷吸收途径的实验研究。
Environ Health Perspect. 1977 Aug;19:173-6. doi: 10.1289/ehp.7719173.
8
Whole-body retention, excretion and metabolism of [74As]arsenic acid in the hamster.[74As]砷酸在仓鼠体内的全身滞留、排泄及代谢
Toxicol Lett. 1980 Mar;5(3-4):175-82. doi: 10.1016/0378-4274(80)90056-9.
9
Metabolism and excretion of orally and intraperitoneally administered gallium arsenide in the hamster.仓鼠经口和腹腔注射砷化镓后的代谢与排泄
Toxicology. 1986 Sep;40(3):237-46. doi: 10.1016/0300-483x(86)90056-9.
10
Anti-oxidant Effect of High Dilutions of , and in Microglial Cells .高稀释度的[具体物质1]、[具体物质2]和[具体物质3]在小胶质细胞中的抗氧化作用 。
Dose Response. 2022 Jun 29;20(2):15593258221103698. doi: 10.1177/15593258221103698. eCollection 2022 Apr-Jun.

引用本文的文献

1
A homeopathic remedy from arnica, marigold, St. John's wort and comfrey accelerates in vitro wound scratch closure of NIH 3T3 fibroblasts.顺势疗法制剂由山金车、金盏花、贯叶连翘和紫草组成,可加速 NIH 3T3 成纤维细胞体外划痕伤口闭合。
BMC Complement Altern Med. 2012 Jul 18;12:100. doi: 10.1186/1472-6882-12-100.
2
Reporting experiments in homeopathic basic research (REHBaR)--a detailed guideline for authors.顺势疗法基础研究中的实验报告(REHBaR)——作者详细指南
Homeopathy. 2009 Oct;98(4):287-298. doi: 10.1016/j.homp.2009.09.006.
3
Can administration of potentized homeopathic remedy, Arsenicum album, alter antinuclear antibody (ANA) titer in people living in high-risk arsenic contaminated areas? I. A correlation with certain hematological parameters.
服用高稀释度顺势疗法药物白砷剂,能否改变生活在高风险砷污染地区人群的抗核抗体(ANA)滴度?I. 与某些血液学参数的相关性。
Evid Based Complement Alternat Med. 2006 Mar;3(1):99-107. doi: 10.1093/ecam/nek013. Epub 2006 Jan 23.
4
Can homeopathic arsenic remedy combat arsenic poisoning in humans exposed to groundwater arsenic contamination?: a preliminary report on first human trial.顺势疗法砷剂能否对抗因接触地下水砷污染而中毒的人类?:首例人体试验的初步报告。
Evid Based Complement Alternat Med. 2005 Dec;2(4):537-48. doi: 10.1093/ecam/neh124. Epub 2005 Oct 19.
5
Towards understanding molecular mechanisms of action of homeopathic drugs: an overview.关于顺势疗法药物作用分子机制的理解概述
Mol Cell Biochem. 2003 Nov;253(1-2):339-45. doi: 10.1023/a:1026048907739.
6
Ameliorating effect of microdoses of a potentized homeopathic drug, Arsenicum Album, on arsenic-induced toxicity in mice.微量增效顺势疗法药物白砷对小鼠砷中毒的改善作用。
BMC Complement Altern Med. 2003 Oct 22;3:7. doi: 10.1186/1472-6882-3-7.
7
Comparative efficacy of two microdoses of a potentized homoeopathic drug, Cadmium Sulphoricum, in reducing genotoxic effects produced by cadmium chloride in mice: a time course study.两种微剂量的强效顺势疗法药物硫酸镉在减轻氯化镉对小鼠产生的遗传毒性作用方面的比较疗效:一项时间进程研究。
BMC Complement Altern Med. 2001;1:9. doi: 10.1186/1472-6882-1-9. Epub 2001 Nov 23.
8
Drop of the weak stuff.倒掉淡的东西。
BMJ. 1988 Sep 3;297(6648):618. doi: 10.1136/bmj.297.6648.618.
9
A controlled evaluation of a homoeopathic preparation in the treatment of influenza-like syndromes.顺势疗法制剂治疗流感样综合征的对照评估。
Br J Clin Pharmacol. 1989 Mar;27(3):329-35. doi: 10.1111/j.1365-2125.1989.tb05373.x.
10
Survey of the use of homeopathic medicine in the UK health system.英国医疗体系中顺势疗法药物使用情况调查。
J R Coll Gen Pract. 1989 Dec;39(329):503-6.