Fujiyoshi K, Suga H, Okamoto K, Nakamura S, Kameyama M
J Neurol Neurosurg Psychiatry. 1987 Jul;50(7):929-32. doi: 10.1136/jnnp.50.7.929.
Arginine-vasopressin (AVP) concentrations in five cortical areas were measured post mortem in nine patients with senile dementia of Alzheimer's type (SDAT), and compared with the control group of comparable ages. In SDAT patients, AVP was significantly reduced in Brodmann areas 4, 7 and 10 (p less than 0.05). In areas 17 and 22, the detectability and the mean concentrations of AVP were also lower than those of control patients, although not significantly.
对9例阿尔茨海默型老年痴呆症(SDAT)患者死后测量了五个皮质区域的精氨酸加压素(AVP)浓度,并与年龄相仿的对照组进行了比较。在SDAT患者中,布罗德曼4区、7区和10区的AVP显著降低(p<0.05)。在17区和22区,AVP的可检测性和平均浓度也低于对照患者,尽管差异不显著。