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应激性糖尿病:综述

Stress-Induced Diabetes: A Review.

作者信息

Sharma Kapil, Akre Shivani, Chakole Swarupa, Wanjari Mayur B

机构信息

Medicine, Jawaharlal Nehru Medical College, Datta Meghe Institute of Medical Sciences, Wardha, IND.

Community Medicine, Jawaharlal Nehru Medical College, Datta Meghe Institute of Medical Sciences, Wardha, IND.

出版信息

Cureus. 2022 Sep 13;14(9):e29142. doi: 10.7759/cureus.29142. eCollection 2022 Sep.

Abstract

It has long been established that stress has a significant impact on metabolic function. Type 2 diabetes may be initiated by psychological and physical stress. The central and peripheral nervous systems are both involved in the neuroendocrine framework that underlies the underlying processes. The release of catecholamines and a rise in serum glucocorticoid concentrations caused by psychological stress enhance the requirement for insulin and insulin resistance. Experiencing persistent hyperglycemia in people with diabetes may be influenced by stress. Blood sugar levels may rise due to hormones being released in response to stress. Although this has adaptive significance in a healthy patient, in the long run, it can cause insulin resistance and lead to diabetes. Additionally, diabetes may cause abnormalities in the regulation of these stress hormones.

摘要

长期以来,人们已经确定压力对代谢功能有重大影响。2型糖尿病可能由心理和身体压力引发。中枢神经系统和外周神经系统都参与了构成潜在过程基础的神经内分泌框架。心理压力导致的儿茶酚胺释放和血清糖皮质激素浓度升高会增加对胰岛素的需求并导致胰岛素抵抗。糖尿病患者持续出现高血糖可能受到压力的影响。由于应激反应释放的激素,血糖水平可能会升高。虽然这在健康患者中具有适应性意义,但从长远来看,它会导致胰岛素抵抗并引发糖尿病。此外,糖尿病可能导致这些应激激素调节异常。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1fbf/9561544/1e20a1dba66c/cureus-0014-00000029142-i01.jpg

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