Hange Namrata, Poudel Sujan, Ozair Saleha, Paul Trissa, Nambakkam Meghna, Shrestha Rakchhya, Greye Farrah, Shah Sangam, Raj Adhikari Yagya, Thapa Sangharsha, Patel Pooja
National University of Singapore, Singapore.
National Medical College, Tribhuvan University, Birgunj, Nepal.
Neurol Res Int. 2022 Oct 12;2022:8336561. doi: 10.1155/2022/8336561. eCollection 2022.
Neuropathic pain affects 7-10% of the population, with most of the patients receiving inadequate and incomplete treatment. Owing to the high financial burden and the poor quality of life of the patients and their caretakers, there is a dire need to address the challenges in diagnosing and treating chronic neuropathic pain.
This literature review was conducted to review novel treatments and related challenges through a systematic search from sources such as PubMed, Google Scholar with the combination of MESH words such as neuropathic pain, management of neuropathic pain. Articles from non-English literature, reports without human subjects, animal studies, and abstracts/posters were excluded. However, human studies and studies published in English were included.
This review article discusses novel treatment modalities while acknowledging the challenges medical workers face while encountering neuropathic pain. Despite the recent advances in diagnosis and treatment modalities, several challenges still exist. Hence, there is still a need to explore the various treatment modalities, emphasizing the cause and underlying pathophysiology of neuropathic pain.
We recommend integrated multimodal treatment with the current treatment facility, including various medical disciplines. However, a personalized approach would work the best depending on the 'patient's medical history. Therefore, this article recommends an integrated, cause-specific, cost-effective approach to address this problem of chronic neuropathic pain.
神经性疼痛影响着7%至10%的人群,大多数患者接受的治疗不足且不完整。由于患者及其照料者的经济负担沉重且生活质量低下,迫切需要应对慢性神经性疼痛诊断和治疗方面的挑战。
进行这项文献综述,通过从PubMed、谷歌学术等来源进行系统检索,并结合诸如神经性疼痛、神经性疼痛管理等医学主题词,来回顾新型治疗方法及相关挑战。排除非英文文献、无人类受试者的报告、动物研究以及摘要/海报。然而,纳入了人类研究和英文发表的研究。
这篇综述文章在承认医护人员在面对神经性疼痛时所面临挑战的同时,讨论了新型治疗方式。尽管在诊断和治疗方式方面取得了最新进展,但仍存在一些挑战。因此,仍有必要探索各种治疗方式,强调神经性疼痛的病因和潜在病理生理学。
我们建议结合当前的治疗设施,包括各个医学学科,采用综合多模式治疗。然而,根据患者的病史,个性化方法效果最佳。因此,本文建议采用一种综合、针对病因、具有成本效益的方法来解决慢性神经性疼痛问题。